Proteome analysis of human postmortem brain tissues in tauopathies, including corticobasal degeneration, progressive supranuclear palsy, and Alzheimer's disease

ABSTRACT: Tauopathies are a group of neurodegenerative diseases characterised by the abnormal accumulation of tau protein within neural and glial cells. The molecular mechanisms of tauopathies remain poorly understood. To identify proteins whose abundance is altered by the disease group, we performed a proteomic analysis of brain homogenate from patients with three tauopathy-related diseases: corticobasal degeneration, progressive supranuclear palsy and Alzheimer's disease.

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Takeshi Ikeuchi 

PROVIDER: PXD072806 | JPOST Repository | Sat May 09 00:00:00 BST 2026

REPOSITORIES: jPOST