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TranscriptomicsGene expression changes resulting from the stable loss of BAP1 in uveal melanoma cell lines
Uveal melanoma is a highly aggressive cancer with a strong propensity for metastasis, yet little is known about the biological mechanisms underlying this metastatic potential. We recently showed that most metastasizing uveal melanomas, which exhibit a class 2 gene expression profile, contain inactiv...
ORGANISM(S): Homo sapiens 
2013-09-06 | E-GEOD-48863 | biostudies-arrayexpress
TranscriptomicsGlobal expression analysis of BAP1 knockdown in transfected 92.1 cells
Analysis of the effect that reduced BAP1 levels have on global gene expression.The hypothesis tested was that reduction in BAP1 levels would produce changes in gene expression similar to changes observed in class 2 uveal melanomas. Data provided insight into genes that are disrupted with reduced BAP...
ORGANISM(S): Homo sapiens 
2011-01-06 | E-GEOD-24896 | biostudies-arrayexpress
UnknownPrognostic Implications of Tumor Diameter in Association With Gene Expression Profile for Uveal Melanoma.
Not available
S-EPMC4966166 | biostudies-literature
TranscriptomicsChromosomal changes in primary human uveal melanomas [RPCI]
Uveal melanoma is the most common cancer of the eye arising from melanocytes within the choroid, ciliary bodies and iris. Almost half of uveal melanomas metastasize hematogenously to distant organs, most often the liver, where the disease becomes fatal. One of the first genetic alterations to be i...
ORGANISM(S): Homo sapiens 
2012-12-06 | E-GEOD-42738 | biostudies-arrayexpress
TranscriptomicsChromosomal changes in primary human uveal melanomas [UCSF]
Uveal melanoma is the most common cancer of the eye arising from melanocytes within the choroid, ciliary bodies and iris. Almost half of uveal melanomas metastasize hematogenously to distant organs, most often the liver, where the disease becomes fatal. One of the first genetic alterations to be i...
ORGANISM(S): Homo sapiens 
2012-12-06 | E-GEOD-42739 | biostudies-arrayexpress
TranscriptomicsChromosomal changes in primary human uveal melanomas
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-12-06 | E-GEOD-42740 | biostudies-arrayexpress
UnknownARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma.
Not available
S-EPMC5027844 | biostudies-literature
UnknownOligogenic genetic variation of neurodegenerative disease genes in 980 postmortem human brains.
Not available
S-EPMC6204946 | biostudies-literature
UnknownASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis.
Not available
S-EPMC5249256 | biostudies-literature
UnknownThe deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.
Not available
S-EPMC3376394 | biostudies-literature
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