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MetabolomicsSpecific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in Nicotiana attenuata
The native diploid tobacco Nicotiana attenuata produces abundant, potent anti-herbivore defense metabolites known as 17-hydroxygeranyllinalool diterpene glycosides (HGL-DTGs) whose glycosylation and malonylation biosynthetic steps are regulated by jasmonate signaling. To characterize the biosyntheti...
2021-10-06 | MTBLS1819 | MetaboLights
TranscriptomicsWhole blood mRNA transcription profiling of host immune changes in neonatal sepsis during vancomycin therapy
The purpose of this study was to investigate changes in host gene expression profiles of neonatal infants with sepsis prior to the initiation of and during vancomycin therapy, to identify treatment-responsive genes and signature pathways associated with recovery from neonatal sepsis. The study analy...
ORGANISM(S): Homo sapiens 
2025-11-25 | E-MTAB-15687 | biostudies-arrayexpress
TranscriptomicsTranscript profiling of transgenic rice lines where the OsMADS26 gene is over-expressed or down growing cultivated in standard or osmotic stress condition
Functional analyses of MADS-box transcription factors in plants have unraveled their role in major developmental programs (e.g; flowering and floral organ identity), in stress-related developmental processes such as abscission, fruit ripening and senescence and the role of some of them in stress res...
ORGANISM(S): Oryza sativa 
2015-11-20 | E-GEOD-52640 | biostudies-arrayexpress
TranscriptomicsHow does orotic acid affect the growth of R.etli CE3?
Growth inhibition of Rhizobium etli and other organisms by exogenous OA has not been previously reported. We conducted genome-wide transcriptomic analysis to determine the possible mechanism by which OA exerts its growth-inhibitory effect on R. etli CE3. The observed changes fall into several broa...
ORGANISM(S): Rhizobium etli CFN 42 
2013-10-12 | E-GEOD-46013 | biostudies-arrayexpress
TranscriptomicsBone Morphogenetic Protein Receptor Antagonists Inhibit Growth and Survival of Lung Cancer Cells Expressing Stem Cell Markers Oct4 or Nestin
H1299 cells were stably transfected with the Oct4 promoter/GFP or Nestin promoter/GFP reporter vectors. By FACS, 106 cells expressing high levels of GFP were isolated and placed into cell culture for twenty-four hours. Total RNA was used. Bone morphogenetic proteins (BMP) are aberrantly expressed in...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-49281 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HeLa CD4+ cells transfected with epitope-tagged eTat plasmid, or parental plasmid pCep4
Expression profiles of HeLa CD4+ cells transfected with epitope-tagged eTat plasmid, or parental plasmid pCep4. Cells are unsynchronized and untreated.
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-570 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HeLa CD4+ cells transfected with parental vector pCep4
Expression profiles of HeLa CD4+ cells transfected with parental vector pCep4. Cells are treated with nocodazole and hydroxyurea.
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-572 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of breast cancer samples to predict response to anthracycline/taxane chemotherapy .
EORTC 10994 phase III breast cancer clinical trial comparing FEC (5-fluorouracil, cyclophosphamide, epirubicin) with ET (epirubicin, docetaxel). 161 needle biopsies of locally advanced or large operable breast tumours were hybridised to Affymetrix X3P chips. The array data from the ER negative ...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6861 | biostudies-arrayexpress
UnknownThe Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19.
Not available
S-EPMC9447373 | biostudies-literature
UnknownViral and Host Factors Are Associated With Mortality in Hospitalized Patients With COVID-19.
Not available
S-EPMC11175705 | biostudies-literature
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