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TranscriptomicsTriplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation [RNA-Seq]
Down syndrome (DS) confers a 20-fold increased risk of B cell acute lymphoblastic leukemia (ALL), yet the mechanisms underlying this association are undefined.  We show that triplication of only 31 genes orthologous to the putative DS Critical Region (DSCR) on chr.21q22 is sufficient to promote B ce...
ORGANISM(S): Mus musculus 
2014-04-20 | E-GEOD-48553 | biostudies-arrayexpress
UnknownImplementation Of New Mexico's 'No Behavioral Health Cost Sharing' Law: A Qualitative Study.
Not available
S-EPMC11884875 | biostudies-literature
TranscriptomicsDNA methylation in peripheral blood from individuals with Crohns' disease or ulcerative colitis and normal controls
Genome wide DNA methylation profiling of Crohn's disease, ulcerative colitis, and normal peripheral blood samples. The Illumina Infinium HumanMethylation450 BeadChip v1.1 was used to obtain DNA methylation profiles across 482,421 CpGs in peripheral blood samples. Samples came from 17 Crohn's disease...
ORGANISM(S): Homo sapiens 
2012-04-04 | E-GEOD-32148 | biostudies-arrayexpress
UnknownIn vivo hippocampal subfield volumes in bipolar disorder-A mega-analysis from The Enhancing Neuro Imaging Genetics through Meta-Analysis Bipolar Disorder Working Group.
Not available
S-EPMC8675404 | biostudies-literature
TranscriptomicsRegulation of gene expressions in vivo by anti-VEGF therapy
U87-EV human glioblastoma xenograft tumours is therapeutically treated by bevacizumab, a humanized anti-human VEGF mAb, when tumour is established in BALB/c SCID mice. At the end point, collect tumour samples and extracted total RNA for microarray to investigate the gene profile changes compared to ...
ORGANISM(S): Homo sapiens 
2014-04-25 | E-GEOD-37956 | biostudies-arrayexpress
TranscriptomicsRegulation of gene expressions in vivo by anti-VEGF and anti-Notch therapy [Mouse430_2]
U87-EV human glioblastoma xenograft tumours is therapeutically treated by bevacizumab, a humanized anti-human VEGF mAb, or dibenzazepine (DBZ) when tumour is established in BALB/c SCID mice. At the end point, collect tumour samples and extracted total RNA for microarray to investigate the gene profi...
ORGANISM(S): Mus musculus 
2014-04-25 | E-GEOD-39413 | biostudies-arrayexpress
TranscriptomicsRegulation of gene expressions in vivo by anti-VEGF and anti-Notch therapy [HG-U133_Plus_2]
U87-EV human glioblastoma xenograft tumours is therapeutically treated by bevacizumab, a humanized anti-human VEGF mAb, or dibenzazepine (DBZ), when tumour is established in BALB/c SCID mice. At the end point, collect tumour samples and extracted total RNA for microarray to investigate the gene prof...
ORGANISM(S): Homo sapiens 
2014-04-25 | E-GEOD-39223 | biostudies-arrayexpress
UnknownPrenatal complications are associated with the postnatal airway host response and microbiota in intubated preterm infants.
Not available
S-EPMC6212338 | biostudies-literature
UnknownOrally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain.
Not available
S-EPMC5933862 | biostudies-literature
UnknownCausal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.
Not available
S-EPMC3564800 | biostudies-literature
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