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TranscriptomicsA Signaling Lipid Associated with Alzheimer’s Disease Promotes Mitochondrial Dysfunction
Fundamental changes in the composition and distribution of lipids within the brain are believed to contribute to the cognitive decline associated with Alzheimer’s disease (AD). The mechanisms by which these changes in lipid composition affect cellular function and ultimately cognition are not well...
ORGANISM(S): Saccharomyces cerevisiae 
2016-01-21 | E-GEOD-40814 | biostudies-arrayexpress
TranscriptomicsRoles for microRNAs, miR-93 and miR-130b, and TP53INP1 tumor suppressor in cell growth dysregulation by HTLV-1
This is to study the role of miRNAs in human T-cell leukemia virus-1, HTLV-1. In this study, we profiled the miRNA expression in virus transformed human cell lines and primary peripheral blood mononuclear cells (PBMCs) from Adult-T cell leukemia (ATL) patients using the RNA-primed, array-based Kleno...
ORGANISM(S): Homo sapiens 
2008-06-06 | E-GEOD-11577 | biostudies-arrayexpress
UnknownStructure of the 1,4-Bis(2'-deoxyadenosin-N(6)-yl)-2S,3S-butanediol intrastrand DNA cross-link arising from butadiene diepoxide in the human N-ras codon 61 sequence.
Not available
S-EPMC2597494 | biostudies-literature
MetabolomicsAnalysis of sex-specific lipid metabolism of Plasmodium falciparum points to the importance of sphingomyelin for gametocytogenesis
Male and female Plasmodium falciparum gametocytes are the parasite lifecycle stage responsible for transmission of malaria from the human host to the mosquito vector. Not only are gametocytes able to survive in radically different host environments, but they are also precursors for male and female g...
2022-04-05 | MTBLS4137 | MetaboLights
UnknownThe association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia.
Not available
S-EPMC3831541 | biostudies-literature
TranscriptomicsA genome-wide analysis of open chromatin in human epididymis epithelial cells reveals novel candidate regulatory elements for male infertility [Transcriptome data]
The epithelium lining the epididymis has a pivotal role in ensuring a luminal environment that can support normal sperm maturation. Many of the individual genes that encode proteins involved in establishing the epididymal luminal fluid are well characterized. They include ion channels, ion exchanger...
ORGANISM(S): Homo sapiens 
2013-09-06 | E-GEOD-50605 | biostudies-arrayexpress
UnknownEfficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies.
Not available
S-EPMC6601548 | biostudies-literature
MetabolomicsImpact of acute lymphoblastic leukemia induction therapy: findings from metabolomics on non-fasted plasma samples from a biorepository

INTRODUCTION: Acute lymphoblastic leukemia (ALL) is among the most common cancers in children. With improvements in combination chemotherapy regimens, the overall survival has increased to over 90%. However, the current challenge is to mitigate adverse events resulting from the c...

2021-08-12 | MTBLS2394 | MetaboLights
ProteomicsComparative exo-proteomic analysis of Trichoderma antagonists induced by oomycete mycelium highlights diverse antagonism strategies
Plant-beneficial fungi from the genus Trichoderma (Hypocreales, Ascomycota) can control oomyceteous plant-pathogenic Pythium myriotylum (Peronosporales, Oomycota) and thus serve as bioeffectors for the eco-friendly products of crop protection. However, the underlying mechanisms of microbe-microbe in...
ORGANISM(S): Trichoderma asperellum CBS 433.97 Trichoderma virens Gv29-8 Hypocrea jecorina (strain QM6a) (Trichoderma reesei) Trichoderma atroviride IMI 206040 Trichoderma parepimyces Trichoderma guizhouense 
2024-07-19 | PXD051895 | Pride
Trichoderma Exo-proteins Hydrolyase Antagonism 
TranscriptomicsEts homologous factor regulates pathways controlling response to injury in Calu-3 airway epithelial cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-12-23 | E-GEOD-63400 | biostudies-arrayexpress
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