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TranscriptomicsDynamic changes in gene expression in vivo predict prognosis of tamoxifen-treated patients with breast cancer
Tamoxifen is the most widely prescribed anti-estrogen treatment for patients with ER-positive breast cancer. However, there is still a need for biomarkers that reliably predict endocrine sensitivity in breast cancers and these may well be expressed in a dynamic manner. In this study we assessed ge...
ORGANISM(S): Homo sapiens 
2010-06-17 | E-GEOD-22386 | biostudies-arrayexpress
UnknownConvergent expansions of keystone gene families drive metabolic innovation in a major eukaryotic clade.
Not available
S-EPMC11291092 | biostudies-literature
UnknownSaccharomycotina yeasts defy long-standing macroecological patterns.
Not available
S-EPMC10927492 | biostudies-literature
UnknownSaccharomycotina yeasts defy longstanding macroecological patterns.
Not available
S-EPMC10491267 | biostudies-literature
MetabolomicsHERPES SIMPLEX VIRUS TYPE 1 IMPAIRS DENDRITIC CELL FUNCTION BY REMODELLING NEUTRAL LIPID METABOLISM AND INDUCING LIPID DROPLET ACCUMULATION
Herpes simplex virus type 1 (HSV-1) infects dendritic cells (DCs), professional antigen-presenting cells that initiate and regulate host antiviral responses. HSV-1 infects DCs limiting their maturation, migration to draining lymph nodes and T cell activation capacity, ultimately promotes their apopt...
2025-04-03 | MTBLS5163 | MetaboLights
UnknownHippocampal thinning linked to longer TOMM40 poly-T variant lengths in the absence of the APOE ε4 variant.
Not available
S-EPMC5496778 | biostudies-literature
ProteomicsDefining mechanisms of multifunctionality in the rabies virus P protein: key roles of conformational diversity and RNA interaction in forming host interfaces
Rabies virus (RABV) is the causative agent of rabies, a severe neurological disease with a 100% fatality rate for symptomatic infection with no therapeutic options. After invading a cell, the rabies virus interacts extensively with host proteins to replicate within the host and circumvent antiviral ...
ORGANISM(S): Lyssavirus rabies Rabies virus CVS-11 
2025-10-10 | PXD064535 | Pride
Phosphoprotein Xl-ms Rabies virus 
UnknownConvergent expansions of keystone gene families drive metabolic innovation in Saccharomycotina yeasts.
Not available
S-EPMC12167968 | biostudies-literature
ProteomicsQuantitative interactome profiling of rabies virus P-protein isoforms P1 and P3
RNA viruses must achieve complex replication and immune evasion functions using limited coding capacity. The rabies virus P protein is a multifunctional viral protein expressed in multiple isoforms via alternative translation. In this study, we investigate how structural and functional diversity ari...
ORGANISM(S): Lyssavirus rabies Homo sapiens (Human) 
2025-10-10 | PXD064752 | Pride
Isoform specificity Membraneless organelles Proteomics Llps Mass spectrometry P protein Ip-ms Viral-host interactions Immunoprecipitation Rabies virus Interactome 
UnknownConformational dynamics, RNA binding, and phase separation regulate the multifunctionality of rabies virus P protein.
Not available
S-EPMC12589655 | biostudies-literature
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