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TranscriptomicsTranscription profiling of Pseudomonas aeruginosa of the sulfate starvation response
Gene expression in response to changes in sulfur supply was studied in P. aeruginosa E601, a cystic fibrosis isolate that displays mucin sulfatase activity, and in P. aeruginosa PAO1. A large family of genes was found to be upregulated by sulfate limitation in both isolates, encoding sulfatases and ...
ORGANISM(S): Pseudomonas aeruginosa 
2008-06-16 | E-GEOD-8408 | biostudies-arrayexpress
UnknownAir Pollutants and Breast Cancer Risk: A Parallel Analysis of Five Large US Prospective Cohorts.
Not available
S-EPMC12614024 | biostudies-literature
UnknownPeripherin is a biomarker of axonal damage in peripheral nervous system disease.
Not available
S-EPMC10629771 | biostudies-literature
MetabolomicsGrowth control of the eukaryote cell: a systems biology study in yeast
Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rate) on the transcriptome, proteome, endometabolome and exometabolome of the yeast Saccharomyces cerevisiae. Each function...
2012-04-19 | MTBLS8 | MetaboLights
GenomicsApplication of Microdroplet PCR for Large-Scale Targeted Bisulfite Sequencing
Cytosine methylation of DNA CpG dinucleotides in gene promoters is an epigenetic modification that regulates gene transcription. While many methods exist to interrogate methylation states, no current methods offer large-scale, targeted, single CpG resolution. We report an approach combining bisulf...
ORGANISM(S): Homo sapiens 
2011-06-25 | E-GEOD-30179 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of trf3 morpholino treated zebrafish embryos to identify Trf3 target genes
To identify Trf3 target genes, we performed expression profiling in trf3 MO-treated embryos (at 6 hpf) using a zebrafish oligonucleotide microarray representing ~12,800 genes.
ORGANISM(S): Danio rerio 
2007-10-29 | E-MEXP-1279 | biostudies-arrayexpress
TranscriptomicsHigh-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities
The ability to perturb genes in human cells is crucial for elucidating gene function and holds great potential for finding therapeutic targets for diseases such as cancer. To extend the catalog of human core and context- dependent fitness genes, we have developed a high-complexity second-generation ...
ORGANISM(S): Homo sapiens 
2015-11-25 | E-GEOD-75189 | biostudies-arrayexpress
TranscriptomicsRNA-Seq characterization of human H1-derived NPC differentiation timecourse
High resolution transcriptional profiling of H1-derived human neuronal precursor cells over a timecourse of differentiation in vitro. Human NPC differentiation timecourse covers Days 0,1,2,4,5,11, and 18 after induction of neuronal differentiation as described in manuscript. Each time point was assa...
ORGANISM(S): Homo sapiens 
2014-04-15 | E-GEOD-56785 | biostudies-arrayexpress
UnknownTocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC8084355 | biostudies-literature
UnknownAdding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial.
Not available
S-EPMC7616360 | biostudies-literature
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