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TranscriptomicsInfluence of RNA Labeling on Expression Profiling of MicroRNAs
Several technical parameters are now being optimized for microRNA expression profiling experiments, but the finite amount of total RNA available continues to bottleneck clinical investigations. We used microarrays to determine the influence of the labeling reagent on total RNA requirements and data ...
ORGANISM(S): synthetic construct 
2012-05-21 | E-GEOD-30045 | biostudies-arrayexpress
ProteomicsThe previously uncharacterized YlxR (RnpM) protein modulates the activity of ribonuclease P
Even though Bacillus subtilis is one of the most studied organisms, no function has been identified for about 20% of its proteins. Among these unknown proteins are several RNA- and ribosome-binding proteins suggesting that they exert functions in cellular information processing. In this work, we hav...
ORGANISM(S): Bacillus subtilis 
2024-06-16 | PXD043900 | Pride
Bacillus subtilis Protein-rna crosslinking 
UnknownComplement Activation via the Lectin and Alternative Pathway in Patients With Severe COVID-19.
Not available
S-EPMC8884149 | biostudies-literature
UnknownThe previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in Bacillus subtilis in vitro.
Not available
S-EPMC10853771 | biostudies-literature
UnknownBrevundimonas and Serratia as host systems for assessing associated environmental viromes and phage diversity by complementary approaches.
Not available
S-EPMC10070969 | biostudies-literature
UnknownCell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD
Not available
S-SCDT-EMBOJ-2019-102811 | biostudies-other
ProteomicsAn Outer Membrane Protein-Targeting Antibiotic Against Resistant Gram-Negative Bacterial Pathogens
There is an urgent need for novel antibiotics against carbapenem and 3rd generation cephalosporin-resistant Gram-negative pathogens, for which the last-resort antibiotics have lost most of their efficacy. We describe here a novel class of synthetic antibiotics that was inspired from natural product-...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2020-02-04 | MSV000084899 | MassIVE
TranscriptomicsLoss of ATM accelerates pancreatic cancer formation and epithelial–mesenchymal transition
Pancreatic ductal adenocarcinoma (PDAC) is associated with accumulation of particular oncogenic mutations and recent genetic sequencing studies have identified ataxia telangiectasia-mutated (ATM) mutations in PDAC cohorts. Here we report that conditional deletion of ATM in a mouse model of PDAC indu...
ORGANISM(S): Mus musculus 
2015-08-07 | E-GEOD-68808 | biostudies-arrayexpress
UnknownImpairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
Not available
S-EPMC9664128 | biostudies-literature
UnknownLow penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.
Not available
S-EPMC3140824 | biostudies-literature
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