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MetabolomicsJ-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis
1H nuclear magnetic resonance (NMR) spectroscopy-based metabolic phenotyping is now widely used for large-scale epidemiological applications. To minimize signal overlap present in 1D 1H NMR spectra, we have investigated the use of 2D J-resolved (JRES) 1H NMR spectroscopy for large-scale phenotyping ...
2018-07-23 | MTBLS540 | MetaboLights
UnknownInhibition of glial D-serine release rescues synaptic damage after brain injury.
Not available
S-EPMC9305835 | biostudies-literature
UnknownBifenthrin causes transcriptomic alterations in mTOR and ryanodine receptor-dependent signaling and delayed hyperactivity in developing zebrafish (Danio rerio).
Not available
S-EPMC5992106 | biostudies-literature
TranscriptomicsEffect of spermine oxidase overexpression on skeletal muscle mRNA expression.
For additional details see Bongers et al, Spermine Oxidase Maintains Basal Skeletal Muscle Gene Expression and Fiber Size, and Is Strongly Repressed by Conditions that Cause Skeletal Muscle Atrophy . Am J Physiol Endocrinol Metab. 2014 [under review] Bilateral tibialis anterior muscles of C57BL/6 m...
ORGANISM(S): Mus musculus 
2014-12-04 | E-GEOD-63006 | biostudies-arrayexpress
TranscriptomicsEffect of p21 overexpression on skeletal muscle mRNA expression.
For additional details see Bongers et al, Spermine Oxidase Maintains Basal Skeletal Muscle Gene Expression and Fiber Size, and Is Strongly Repressed by Conditions that Cause Skeletal Muscle Atrophy . Am J Physiol Endocrinol Metab. 2014 [under review] Bilateral tibialis anterior muscles of C57BL/6 m...
ORGANISM(S): Mus musculus 
2014-12-04 | E-GEOD-63007 | biostudies-arrayexpress
MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
UnknownDevelopmental exposure to environmentally relevant concentrations of bifenthrin alters transcription of mTOR and ryanodine receptor-dependent signaling molecules and impairs predator avoidance behavior across early life stages in inland silversides (Menidia beryllina).
Not available
S-EPMC6464817 | biostudies-literature
TranscriptomicsRole of Aldoketoreductases and Other Doxorubicin Pharmacokinetic Genes in Doxorubicin Resistance, DNA binding, and Subcellular Localization
Objective: To assess the role of aldoketoreductases and other doxorubicin pharmacokinetic or pharmacogenomic genes in doxorubicin cytotoxicity, resistance, DNA binding activity, and subcellular localization, Methods: We conducted a whole genome microarray study to identify differences in betwee...
ORGANISM(S): Homo sapiens 
2012-11-22 | E-GEOD-27254 | biostudies-arrayexpress
UnknownAntibody production using a ciliate generates unusual antibody glycoforms displaying enhanced cell-killing activity.
Not available
S-EPMC5098438 | biostudies-literature
TranscriptomicsProteomic view of the Plasmodium falciparum life cycle
The completion of the Plasmodium falciparum clone 3D7 genome provides a basis on which to conduct comparative proteomics studies of this human pathogen. Here, we applied a high-throughput proteomics approach to identify new potential drug and vaccine targets and to better understand the biology of t...
ORGANISM(S): Plasmodium falciparum 3D7 
2002-12-22 | E-GEOD-92 | biostudies-arrayexpress
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