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ProteomicsCombining high resolution and exact calibration to boost statistical power: A well-calibrated score function for high-resolution MS2
This project reanalzyes data from 4 other projects. Information about the samples can be found in the following four publications. The four samples used in this study include a ocean metaproteome sample, a human sample, a E. coli sample, and a Plamodium falciparum sample. B. N. Pease, E. L. Huttli...
ORGANISM(S): Homo sapiens (Human) Plasmodium falciparum (isolate 3D7) Escherichia coli 
2018-09-19 | PXD009265 | Pride
E. coli Score function Ocean Human Plasmodium 
TranscriptomicsInvestigation of the gene expression profile of LYVE-1-positive macrophages
LYVE-1-positive macrophages were observed to be closely spatially associated with the developing lymphatic vasculature. The role of this population of macrophages in the embryo is uncharacterised. We used microarray analyses to investigate which genes are differentially regulated between LYVE-1-posi...
ORGANISM(S): Mus musculus 
2010-10-02 | E-GEOD-24492 | biostudies-arrayexpress
TranscriptomicsComparison of KrasG12D/WT;p53Fx/Fx and KrasG12D/G12D;p53Fx/Fx MEFs
Microarray expression data generated to compare the biological impact of KrasG12D allelic duplication in p53null mouse embryonic fibroblasts (MEFs). The RAS/MAPK-signalling pathway is frequently deregulated in non-small cell lung cancer (NSCLC), often through activating mutations in KRAS. Mouse mode...
ORGANISM(S): Mus musculus 
2016-02-24 | E-GEOD-75871 | biostudies-arrayexpress
UnknownHif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction.
Not available
S-EPMC9021927 | biostudies-literature
ProteomicsRuegeria pomeroyi growth curve
The ubiquitous heterotrophic marine bacterium, Rugeria pomeroyi, was experimentally cultured under both environmentally realistic carbon conditions and with a tracer-level addition of 13C-labeled leucine. Bacterial protein biosynthesis was tracked through exponential and stationary growth phases. Th...
ORGANISM(S): Ruegeria pomeroyi 
2019-07-31 | PXD008661 | Pride
Ruegeria pomeroyi Growth curve Bacteria 13c leucine 
ProteomicsFunctional Response of Polar Bacterial Communities under Variable Organic Inputs Revealed with Metaproteomic, 16S rRNA and Organic Compositional Analysis
Organic matter recycling in marine systems is largely driven by microbial processes, particularly in the Arctic where primary production and inputs can be temporally offset from upper trophic level consumption. This study followed bacterial dynamics in the chlorophyll maximum of the Bering Strait an...
ORGANISM(S): marine metagenome 
2019-02-18 | PXD008780 | Pride
Metaproteomics Metagenomics Bacteria Arctic Organic matter 
TranscriptomicsExploring the role of sigma factor gene expression on production by Corynebacterium glutamicum: sigma factor H and FMN as example
Bacteria are known to cope with environmental changes by using alternative sigma factors binding to RNA polymerase core enzyme. Sigma factor is one of the targets to modify transcription regulation in bacteria and to influence production capacities. In this study, the effect of overexpressing all an...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2015-06-20 | E-GEOD-70017 | biostudies-arrayexpress
ProteomicsDetection of Low Abundance Ocean Bacterial Peptides DDA
Bacteria transform nutrients and degrade organic matter, making them an essential part of healthy ecosystems. By assaying bacterial physiology within a complex system, the status of the whole ecosystem can be investigated. Proteins are the dynamic molecules that control essential bacterial physiolog...
ORGANISM(S): Ruegeria pomeroyi Thalassiosira pseudonana 
2017-02-01 | PXD004799 | Pride
Proteomics Ruegeria pomeroyi Thalassiosira pseudonana Ocean bacteria Dda 
ProteomicsDetection of Low Abundance Ocean Bacterial Peptides DIA
Bacteria transform nutrients and degrade organic matter, making them an essential part of healthy ecosystems. By assaying bacterial physiology within a complex system, the status of the whole ecosystem can be investigated. Proteins are the dynamic molecules that control essential bacterial physiolog...
ORGANISM(S): Ruegeria pomeroyi 
2017-02-02 | PXD004758 | Pride
Srm Proteomics Ruegeria pomeroyi Dia Bacteria Ocean 
TranscriptomicsTranscription profiling of mouse colon carcinomas over-expressing c-Myc
MycRas vs Ras colon carcinoma. Human adenocarcinomas commonly harbor mutations in the Ki-Ras and c-Myc proto-oncogenes and the trp53 tumor suppressor gene. All three genetic lesions are potentially pro-angiogenic, since they sustain production of the vascular endothelial growth factor (VEGF). Yet m...
ORGANISM(S): Mus musculus 
2006-09-08 | E-MEXP-757 | biostudies-arrayexpress
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