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MetabolomicsLipidCreator workbench to probe the lipidomic landscape - Targeted lipidomics analysis of Human Plasma samples and comparison with NIST SRM 1950 standard

Here we present LipidCreator, a software that fully supports targeted lipidomics assay development. LipidCreator offers a comprehensive framework to compute MS/MS fragment masses for over 60 lipid classes. LipidCreator provides all functionalities needed to define fragments, manage stable isotope...

2020-04-15 | MTBLS1375 | MetaboLights
MetabolomicsSRM1957 validation using GC-XLE
Not available
ORGANISM(S): Homo sapiens 
ST001797 | MetabolomicsWorkbench
MetabolomicsSRM1957 validation using GC-XLE (2)
Not available
ORGANISM(S): Homo sapiens 
ST001798 | MetabolomicsWorkbench
MetabolomicsNIST SRM Smoker non-Smoker Urine Comparison
Not available
ORGANISM(S): Homo sapiens 
ST000420 | MetabolomicsWorkbench
MetabolomicsRecovery of internal std in SRM-1957
Not available
ORGANISM(S): Homo sapiens 
ST001799 | MetabolomicsWorkbench
ProteomicsFLNc Calpain GluC SRM Analysis
Human filamin C (FLNc) is a target of the protease calpain at Y2625. To confirm the dependency of calpain cleavage from FLNc phosphorylation at position S2623/S2624 by PKCa, FLNc was overexpressed in HEK293 cells and cells were treated with PMA to stimulated kinase activity, with Gö6976 to inhibit k...
ORGANISM(S): Homo sapiens (Human) 
2017-01-02 | PXD005097 | Pride
Calpain Flnc Srm 
ProteomicsProtein turnover measurement using selected reaction monitoring-mass spectrometry (SRM-MS) C4PR_LIV
Protein turnover represents an important mechanism in the functioning of cells, with deregulated synthesis and degradation of proteins implicated in many diseased states. Therefore, proteomics strategies to measure, with high confidence, turnover rates are of vital importance to understanding many ...
ORGANISM(S): Mus musculus (Mouse) 
2016-08-10 | PXD004413 | Pride
Srm Proteomics Ms1 Mass spectrometry Protein turnover Quantification 
GenomicsSerratia marcescens strain:SRM-1
Serratia marcescens strain:SRM-1 Genome sequencing and assembly
PRJNA437541 | ENA
ProteomicsLFQ and SRM proteome analysis of Saliva reveals transition signatures from health to periodontal disease
Phase 1: The whole saliva samples were obtained from 66 systemically healthy subjects consisting of patients with chronic periodontitis (CP), generalized aggressive periodontitis (G-AgP), gingivitis and individuals with periodontal health. The use of humans for study satisfied the requirements of th...
ORGANISM(S): Homo sapiens (Human) 
2018-04-10 | PXD007535 | Pride
Data integration Lfq Srm Lc-ms/ms 
ProteomicsA Combined Shotgun and Targeted Mass Spectrometry Strategy for Breast Cancer Biomarker Discovery
Metastasizing breast cancer is an incurable disease. Thus, it is important to find proteins responsible for tumor dissemination, which may be used as biomarkers or treatment targets. In this study, we established the combination of a non-targeted LC-MS/MS discovery and a targeted LC-SRM verification...
ORGANISM(S): Homo sapiens (Human) 
2015-06-16 | PXD001685 | Pride
Breast cancer Shotgun Mrm Distant recurrence Srm 
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