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MetabolomicsJ-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis
1H nuclear magnetic resonance (NMR) spectroscopy-based metabolic phenotyping is now widely used for large-scale epidemiological applications. To minimize signal overlap present in 1D 1H NMR spectra, we have investigated the use of 2D J-resolved (JRES) 1H NMR spectroscopy for large-scale phenotyping ...
2018-07-23 | MTBLS540 | MetaboLights
TranscriptomicsPromoter hypermethylation in MLL-r leukemia: biology and therapeutic targeting
MLL-r infant acute lymphoblastic leukemia (ALL) has largely unclear oncogenesis. It has been shown unrelated to copy number change or mutations in the tyrosine kinome. We therefore, explored the possible role of genome wide CpG island hypermethylation in MLL-r infant ALL. We employed the HpaII-ti...
ORGANISM(S): Homo sapiens 
2009-12-29 | E-GEOD-19671 | biostudies-arrayexpress
ModelsIancu2007_CardiacMyoscytes_cAMPsignaling
This a model from the article: Compartmentation of cAMP signaling in cardiac myocytes: a computational study. Iancu RV, Jones SW, Harvey RD. Biophys J 2007 May 1;92(9):3317-31 17293406 , Abstract: Recepto...
2005-01-01 | MODEL1006230117 | BioModels
UnknownPharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue.
Not available
S-EPMC5161516 | biostudies-literature
UnknownThe RD-Connect Genome-Phenome Analysis Platform: Accelerating diagnosis, research, and gene discovery for rare diseases.
Not available
S-EPMC9324157 | biostudies-literature
UnknownProspective International Randomized Phase II Study of Low-Dose Abiraterone With Food Versus Standard Dose Abiraterone In Castration-Resistant Prostate Cancer.
Not available
S-EPMC5941614 | biostudies-literature
MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
TranscriptomicsTranscriptional profiling of FeHm effects on Haemophilus influenzae
Background: Haemophilus influenzae has an absolute aerobic growth requirement for heme and has developed multiple complex mechanisms to obtain this essential nutrient. Although an understanding of the heme acquisition mechanisms of H. influenzae is emerging, significant gaps remain to be elucidated...
ORGANISM(S): Haemophilus influenzae 
2009-01-20 | E-GEOD-11362 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of FeHm effects on Haemophilus influenzae R2866
Background: Haemophilus influenzae has an absolute aerobic growth requirement for heme and has developed multiple complex mechanisms to obtain this essential nutrient. Although an understanding of the heme acquisition mechanisms of H. influenzae is emerging, significant gaps remain to be elucidated...
ORGANISM(S): Haemophilus influenzae R2866 
2009-01-20 | E-GEOD-11349 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of FeHm effects on Haemophilus influenzae 10810
Background: Haemophilus influenzae has an absolute aerobic growth requirement for heme and has developed multiple complex mechanisms to obtain this essential nutrient. Although an understanding of the heme acquisition mechanisms of H. influenzae is emerging, significant gaps remain to be elucidated...
ORGANISM(S): Haemophilus influenzae 
2009-01-20 | E-GEOD-11354 | biostudies-arrayexpress
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