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UnknownWhole Genome Sequencing Analysis of Model Organisms Elucidates the Association Between Environmental Factors and Human Cancer Development.
Determining a novel etiology and mechanism of human cancer requires extraction of characteristic mutational signatures derived from chemical substances. This study explored the mutational signatures of N-nitroso bile acid conjugates using Salmonella strains. Exposing S. typhimurium<...
S-EPMC11508241 | biostudies-literature
UnknownCharacteristic stacked structures and luminescent properties of dinuclear lanthanide complexes with pyrene units.
A novel design strategy of stacked organic fluorophores using dinuclear lanthanide (Ln(III)) complexes is demonstrated for the formation of excimer. The dinuclear Ln(III) complexes are composed of two Ln(III) (Eu(III) or Gd(III)) ions, six hexafluoroacetylacetonate (hfa), and two pyrene-based phosph...
S-EPMC10140548 | biostudies-literature
UnknownThermally-assisted photosensitized emission in a trivalent terbium complex.
Luminescent lanthanide complexes containing effective photosensitizers are promising materials for use in displays and sensors. The photosensitizer design strategy has been studied for developing the lanthanide-based luminophores. Herein, we demonstrate a photosensitizer design using dinuclear lumin...
S-EPMC10287744 | biostudies-literature
UnknownPopulation Pharmacokinetics and Pharmacodynamics of Meropenem in Critically Ill Pediatric Patients.
This study investigates the optimal meropenem (MEM) dosing regimen for critically ill pediatric patients, for which there is a lack of pharmacokinetic (PK) studies. We conducted a retrospective single-center PK and pharmacodynamic (PD) analysis of 34 pediatric intensive care unit patients who receiv...
S-EPMC7848983 | biostudies-literature
UnknownD-loop Mutations in Renal Cell Carcinoma Improve Predictive Accuracy for Cancer-Related Death by Integrating with Mutations in the NADH Dehydrogenase Subunit 1 Gene.
Renal cell carcinoma (RCC) is associated with various genetic alterations. Although whole-genome/exome sequencing analysis has revealed that nuclear genome alterations are associated with clinical outcomes, the association between nucleotide alterations in the mitochondrial genome and RCC clinical o...
S-EPMC6947453 | biostudies-literature
UnknownPreparation of photonic molecular trains via soft-crystal polymerization of lanthanide complexes.
Soft-crystals are defined as flexible molecular solids with highly ordered structures and have attracted attention in molecular sensing materials based on external triggers and environments. Here, we show the soft-crystal copolymerization of green-luminescent Tb(III) and yellow-luminescent Dy(III) c...
S-EPMC9256636 | biostudies-literature
UnknownImpact of tumor contact surface area on collecting system entry in robot-assisted partial nephrectomy: a retrospective analysis.

Background

Collecting system entry in robot-assisted partial nephrectomy may occur even in cases showing a low N factor in the R.E.N.A.L nephrometry score. Therefore, in this study, we focused on the tumor contact surface area with the adjacent renal parenchyma and attempted to construct a n...
S-EPMC10165753 | biostudies-literature
UnknownStructure-changeable luminescent Eu(III) complex as a human cancer grade probing system for brain tumor diagnosis.
Accurate determination of human tumor malignancy is important for choosing efficient and safe therapies. Bioimaging technologies based on luminescent molecules are widely used to localize and distinguish active tumor cells. Here, we report a human cancer grade probing system (GPS) using a water-solu...
S-EPMC10803341 | biostudies-literature
TranscriptomicsTranscription profiling of human gastrointestinal stromal tumor (GIST) reveals gene expression determined distinct classes.
GIST is considered to invariably arise through gain-of-function KIT or PDGFRA mutation of the interstitial cells of Cajal (ICC). However, the genetic basis of the malignant progression of GIST is poorly understood. We analysed the expression levels of 54,613 probe sets in 32 surgical samples of untr...
ORGANISM(S): Homo sapiens 
2008-10-18 | E-GEOD-8167 | biostudies-arrayexpress
UnknownCharge transfer emission between π- and 4f-orbitals in a trivalent europium complex.
Photoinduced metal-to-ligand (or ligand-to-metal) charge-transfer (CT) states in metal complexes have been extensively studied toward the development of luminescent materials. However, previous studies have mainly focused on CT transitions between d- and π-orbitals. Herein, we report the demonstrati...
S-EPMC11775200 | biostudies-literature
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