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ProteomicsInhibition of T cell activation and function by the CIN85 adaptor protein
CIN85 is ubiquitously expressed adaptor protein. In T cells, CIN85 is recruited to the TCR signaling complex and inhibit TCR signaling. To reveal the molecular function of CIN85-mediated inhibition, we performed Flag-CIN85 (CIN85dA) immuno-precipitation and identified the binding proteins. As a nega...
ORGANISM(S): Mus Musculus (mouse) 
2019-01-16 | PXD012369 | JPOST Repository
TranscriptomicsTranscription profiling of mouse SKG FR4-CD4+ cells and age-matched BALB/c FR4-CD4+ cells, and between IFN-g-/- CD4+ cells transferred to RAG2-/- mice and IL-6-/- CD4+ T cells transferred to IL-6-/- RAG2-/- mice
Th17 cells are enriched by sorting FR4-CD4+ T cells from SKG mice. A large number of Th17 cells also develop spontaneously when CD4+ T cells from IFN-g-deficient (IFN-g-/-) BALB/c mice are transferred to T cell-deficient RAG2-deficient (RAG2-/-) mice and subjected to homeostatic proliferation, where...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9316 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Hela cells infected with Trypanosoma cruzi
As Trypanosoma cruzi, the etiological agent of Chagas disease, multiplies in the cytoplasm of nucleated host cells, infection with this parasite is highly likely to affect host cells. We performed an exhaustive transcriptome analysis of T. cruzi-infected HeLa cells using an oligonucleotide microarra...
ORGANISM(S): Homo sapiens 
2008-04-08 | E-GEOD-7047 | biostudies-arrayexpress
ProteomicsArabidopsis Wdr8 interactors identification
To identify Arabidopsis Wdr8 interactors, immunoprecipitation associated LC-MS/MS analysis was carried out. Crude proteins extracted from Wdr8-GFP expressing transgenic plants was subjected to the immuno-precipitation assay using GFP antibody magnetic beads (µMACS GFP isolation kit, Miltenyi Biotec)...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-02-17 | PXD026063 | Pride
Gfp antibody coupled immunoprecipitation Arabidopsis seedlings Lc-ms/ms 
TranscriptomicsA new classification of chromosome instability (CIN) phenotype, CIN-high and CIN-low
Samples were taken from colorectal cancers in surgically resected specimens in 35 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be u...
ORGANISM(S): Homo sapiens 
2012-07-03 | E-GEOD-30540 | biostudies-arrayexpress
UnknownLiver function effects of SGLT2 inhibitor and GLP-1 receptor agonist combination treatment in patients with type 2 diabetes (post hoc analysis of RECAP study).
Not available
S-EPMC12209503 | biostudies-literature
TranscriptomicsGene expression signature and the prediction of liver metastasis in colorectal cancer by DNA microarray
Samples were taken from colorectal cancers in surgically resected specimens in 189 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be ...
ORGANISM(S): Homo sapiens 
2011-08-25 | E-GEOD-14095 | biostudies-arrayexpress
UnknownRenoprotective effects of combination treatment with sodium-glucose cotransporter inhibitors and GLP-1 receptor agonists in patients with type 2 diabetes mellitus according to preceding medication
Not available
S-EPMC10725108 | biostudies-literature
UnknownCorrelation Between Lateralization Index of Adrenal Venous Sampling and Standardized Outcome in Primary Aldosteronism.
Not available
S-EPMC6057509 | biostudies-literature
TranscriptomicsAccumulated α-synuclein affects the progression of GM2 gangliosidoses
The accumulation of α-synuclein (ASyn) has been observed in several lysosomal storage diseases (LSD), but it remains unclear if the accumulation of ASyn contributes to the pathology. The mitochondria degeneration, reduced expression of manganese superoxide dismutase 2, and reactive oxygen species-me...
ORGANISM(S): Mus musculus 
2015-05-12 | E-GEOD-68748 | biostudies-arrayexpress
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