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GenomicsIdentification of transcription factor MAB-5 binding sites
We identified the DNA binding sites of MAB-5 in C. elegans. MAB-5 was C-terminally tagged with GFP and the expression pattern was examined through fluorescent microscopy. The binding sites were determined using chromatin immunoprecipitation with anti-GFP antibody followed by illumina high-throughput...
ORGANISM(S): Caenorhabditis elegans 
2009-04-11 | E-GEOD-15625 | biostudies-arrayexpress
GenomicsGenome-wide identification of the occupancy of RNA polymerase II (POL II) at L4/young adult stage in C. elegans
We acquied the RNA polymerase II binding profiles in ama-1 transgenic worms. The large subuint of POL II, AMA-1, was C-terminally tagged with GFP, the binding regions were determined using chromatin immunoprecipitation with anti-GFP and anti-polymerase II antibodies followed by illumina high-through...
ORGANISM(S): Caenorhabditis elegans 
2009-04-11 | E-GEOD-15535 | biostudies-arrayexpress
GenomicsIdentification of transcription factor DAF-16 binding sites in C. elegans
We identified the DNA binding sites of DAF-16 in transgenic line TJ356 (daf-16::gfp) that carries high-copy number daf-16. The expression pattern was examined through fluorescent microscopy. The binding sites were determined using chromatin immunoprecipitation with anti-GFP antibody and anti-POL II ...
ORGANISM(S): Caenorhabditis elegans 
2009-04-11 | E-GEOD-15567 | biostudies-arrayexpress
GenomicsIdentification of transcription factor DPY-27 binding sites
We identified the DNA binding sites of DPY-27 in C. elegans. DPY-27 was C-terminally tagged with GFP and the expression pattern was examined through fluorescent microscopy. The binding sites were determined using chromatin immunoprecipitation with anti-GFP antibody followed by illumina high-throughp...
ORGANISM(S): Caenorhabditis elegans 
2009-04-03 | E-GEOD-15501 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of TAP::ALG-1 associated RNAs isolated from synchronized 'wild-type' animals and 'mir-58' mutants
To discover new miRNA targets, we generated a C. elegans transgenic line expressing a functional N-terminally Tandem Affinity Purification (TAP) tagged ALG-1 protein (C. elegans strain WS4303). We crossed the TAP::ALG-1 transgene into the mir-58(n4640) mutant background to generate the strain WS5041...
ORGANISM(S): Caenorhabditis elegans 
2012-03-01 | E-GEOD-32942 | biostudies-arrayexpress
TranscriptomicsExpression analysis of WS4303 (wild type) vs WS5041 (mir-58 mutants) total mRNA
To discover new miRNA targets, we generated a C. elegans transgenic line expressing a functional N-terminally Tandem Affinity Purification (TAP) tagged ALG-1 protein (C. elegans strain WS4303). We crossed the TAP::ALG-1 transgene into the mir-58(n4640) mutant background to generate the strain WS5041...
ORGANISM(S): Caenorhabditis elegans 
2012-03-01 | E-GEOD-32943 | biostudies-arrayexpress
TranscriptomicsIdentification of miRNA target genes in C. elegans by RIP-chip-SRM
RIP-chip-SRM : a New Combinatorial Large Scale Approach Identifies a Set of Translationally Regulated bantam/miR 58 Targets in C. elegans RNA binding protein immunopurification + microarray + targeted protein quantification via Selected Reaction Monitoring This SuperSeries is composed of the follow...
ORGANISM(S): Caenorhabditis elegans 
2012-03-01 | E-GEOD-32944 | biostudies-arrayexpress
UnknownLiraglutide and Cardiovascular Outcomes in Type 2 Diabetes.
Not available
S-EPMC4985288 | biostudies-literature
UnknownInitial Invasive or Conservative Strategy for Stable Coronary Disease.
Not available
S-EPMC7263833 | biostudies-literature
UnknownHealth-Status Outcomes with Invasive or Conservative Care in Coronary Disease.
Not available
S-EPMC7261489 | biostudies-literature
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