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TranscriptomicsComprehensive assessment of the regulons controlled by the FixLJ-FixK2-FixK1 cascade in Bradyrhizobium japonicum
Genome-wide transcription profiling of B. japonicum fixJ, fixK2, and fixK1 mutant strains which were grown in free-living microoxic condition, and in the case of the fixK1 mutant also in anoxic condition. Transcriptomes of nodules from soybean plants infected with the fixJ or fixK2 mutant strains we...
ORGANISM(S): Bradyrhizobium japonicum 
2010-05-23 | E-GEOD-12491 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human BJ fibroblasts after LIN-9 depletion by a shRNA
Aim: identification of differentially expressed genes after LIN-9 depletion.

hTERT immortalized human BJ fibroblasts were infected with pMSCV-Blasticidin based retroviruses encoding a shRNA which targets human LIN-9 and the empty vector respectively.
After 4 days of selection total RNA ...
ORGANISM(S): Homo sapiens 
2006-11-23 | E-MEXP-752 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embyronic fibroblasts from wild type and Lin9 knockout strains treated with 4-hydroxytestosterone
We used microarrays to analyze the role of Lin9 in gene expression. Experimental overall design: We prepared MEFs from embyos containing a conditional allele of Lin9 and a CreERT2 transgene. Transcriptional profiles of untreated and 4-OHT-treated MEFs were compared.
ORGANISM(S): Mus musculus 
2010-03-31 | E-MEXP-2097 | biostudies-arrayexpress
UnknownCytogenetic prognostication within medulloblastoma subgroups.
Not available
S-EPMC3948094 | biostudies-literature
UnknownTherapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
Not available
S-EPMC4962737 | biostudies-literature
UnknownCalpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections.
Not available
S-EPMC10584882 | biostudies-literature
Genomicsena-DATASET-MUGQIC-22-03-2014-14:08:20:709-444 - samples
Whole exome sequencing of paediatric glioblastoma with mutations reported in the manuscript: Mutations in ACVR1, FGFR1 and TP53 associate with tumor location in histone H3 K27M pediatric midline high-grade astrocytoma
EGAD00001000792 | EGA
TranscriptomicsFrequent driver mutations in histone H3.3 and chromatin remodeling genes in paediatric glioblastoma
Whole exome sequencing identified frequent driver mutations in a series of paediatric glioblastomas We used microarray-based profiling to investigate differences in gene expression according to mutational status of driver genes RNA from 27 primary tumor samples was subject to QC by Agilent BioAnalys...
ORGANISM(S): Homo sapiens 
2012-03-01 | E-GEOD-34824 | biostudies-arrayexpress
Genomicsena-DATASET-MUGQIC-21-03-2014-16:25:00:707-841 - samples
Exome sequencing of familial and sporadic small cell cancer of ovary cases.
EGAD00001000791 | EGA
GenomicsLocation specific ACVR1, FGFR1 and TP53 mutations in pediatric glioblastomas in conjunction with H3.3 K27M.
Recurrent somatic H3 K27M mutations characterize midline pediatric high-grade astrocytomas (pHGAs). In 40 treatment-naïve midline pHGAs we find additional somatic mutations specific to tumor location. Gain-of-function mutations in ACVR1 occur in tumors of the pons in conjunction with H3.1K27M, whil...
EGAS00001000720 | EGA
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