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TranscriptomicsExpression Data from Memory P14 Tg CD8 T cells after either saline mock-infection, Pichinde Virus Infection (bystander infection) or Pichinde Virus infection with daily treatment with anti-CD122 (clone TM-b1)
Exposure to inflammatory cytokines driven by bystander cytokines can have profound effects on the function of memory CD8 T cells. Here we transferred a 1-5X10^4 of P14 TCR-tg T cells (specific for gp33-41 of LCMV) on day -1 followed by infection with 2X10^5 PFU of LCMV Armstrong ip to generate memor...
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-69791 | biostudies-arrayexpress
UnknownImaging sequence for joint myocardial T1 mapping and fat/water separation.
Not available
S-EPMC6258274 | biostudies-literature
TranscriptomicsWhole genome transcription profile of antigen receptor activated B cells
To search for rapid changes in gene expression following BCR activation, we performed DNA microarray analysis of activated splenic B cells with and without anti-IgM treatment for 3 hour. The expression of a remarkably large set of genes differed significantly. Primary B-lymphocytes were purified fro...
ORGANISM(S): Mus musculus 
2010-05-08 | E-GEOD-15606 | biostudies-arrayexpress
TranscriptomicsWhole genome transcription profile showing early changes in gene expression in antigen receptor activated B cells
To search for rapid changes in gene expression following BCR activation, we performed DNA microarray analysis of activated splenic B cells with and without anti-IgM treatment for 1 and 2 hour. Primary B-lymphocytes were purified from mouse spleens and stimulated with IL-4 (Pepro-Tech) and CD40L (R&D...
ORGANISM(S): Mus musculus 
2012-07-10 | E-GEOD-35748 | biostudies-arrayexpress
TranscriptomicsWhole genome transcription profile of antigen receptor activated B cells expressing wildtype or Calmodulin (CaM) - resistant E12
To elucidate the genome-wide role of Ca2+/ calmodulin inhibition of E2A in regulation of BCR activation, we performed DNA microarray analysis of activated splenic B cells expressing wildtype or CaM-resistant E12 mutant m8N47 with and without anti-IgM treatment for 3 hour.The expression of a remarkab...
ORGANISM(S): Mus musculus 
2012-07-10 | E-GEOD-35747 | biostudies-arrayexpress
GenomicsGenome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis

Monozygotic (MZ) twins have been widely employed for dissection of the relative contributions of genetics and environment in disease. In multiple sclerosis (MS), an autoimmune demyelinating disease that commonly causes neurodegeneration and disability in young adults, disease discordance in M...

phs000239.v2.p1 | EGA
UnknownMetabolic profiling of single cells by exploiting NADH and FAD fluorescence via flow cytometry.
Not available
S-EPMC11300934 | biostudies-literature
UnknownDysregulated lipid and fatty acid metabolism link perfluoroalkyl substances exposure and impaired glucose metabolism in young adults.
Not available
S-EPMC8009052 | biostudies-literature
UnknownCaffeine, creatine, GRIN2A and Parkinson's disease progression.
Not available
S-EPMC5386398 | biostudies-literature
UnknownTherapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
Not available
S-EPMC4962737 | biostudies-literature
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