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TranscriptomicsAPOL1 renal-risk variants induce mitochondrial dysfunction (Affymetrix 2)
To assess differential gene expression by APOL1 renal-risk (2 risk alleles) vs. non-risk (G0G0) genotypes in primary proximal tubule cells (PTCs), global gene expression (mRNA) levels were examined on Affymetrix HTA 2.0 arrays in primary PTCs cultured from non-diseased kidney in African Americans wi...
ORGANISM(S): Homo sapiens 
2016-08-23 | E-GEOD-85920 | biostudies-arrayexpress
TranscriptomicsLudwig Institute/UCSD ENCODE project June 2007 Release
The readout of genome information is controlled by transcriptional regulatory elements, but a comprehensive view of the combinatorial control by these DNA sequences, which bind regulatory protein and/or the modified histones in regulating gene transcription, is clearly preliminary. We have developed...
ORGANISM(S): Homo sapiens 
2007-06-01 | E-GEOD-7872 | biostudies-arrayexpress
UnknownBRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma.
Not available
S-EPMC4356711 | biostudies-literature
UnknownMolecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P component.
Not available
S-EPMC2669789 | biostudies-literature
UnknownRandomized phase I trial HIV-CORE 003: Depletion of serum amyloid P component and immunogenicity of DNA vaccination against HIV-1.
Not available
S-EPMC5957335 | biostudies-literature
TranscriptomicsLudwig Institute/UCSD ENCODE project August 2007 Release
The readout of genome information is controlled by transcriptional regulatory elements, but a comprehensive view of the combinatorial control by these DNA sequences, which bind regulatory protein and/or the modified histones in regulating gene transcription, is clearly preliminary. We have developed...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-8887 | biostudies-arrayexpress
UnknownClinical ApoA-IV amyloid is associated with fibrillogenic signal sequence.
Not available
S-EPMC9291309 | biostudies-literature
TranscriptomicsKnock-out of the nuclear localization in pp65 protein of Cytomegalovirus: biologic and immunologic effects
The CMVpp65 protein contains 2 bipartite nuclear localization signals (NLS) at 415-438aa and 537-561aa near the carboxy terminus of CMVpp65 and a phosphate binding site related to kinase activity at lysine-436. A mutation of pp65 having K436N (CMVpp65mII) and further deletion of aa537-561 resulted ...
ORGANISM(S): Homo sapiens 
2009-01-30 | E-GEOD-14347 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for Diffuse Intrinsic Pontine Glioma
Diffuse intrinsic pontine glioma (DIPG) is one of the most devastating of paediatric malignancies and one for which no effective therapy exists. A major contributor to the failure of therapeutic trials is the assumption that biologic properties of brainstem tumours in children are identical to cereb...
ORGANISM(S): Homo sapiens 
2010-06-16 | E-GEOD-18828 | biostudies-arrayexpress
TranscriptomicsM. sedula transcriptional response under "strict" carbon-limited autotrophy compared to carbon "rich" autotrophy and heterotrophy
Metallosphaera sedula is an extremely thermoacidophilic archaeon that grows heterotrophically on peptides, and chemolithoautotrophically on hydrogen, sulfur, or reduced metals as energy sources. During autotrophic growth, carbon dioxide is incorporated into cellular carbon via the 3-hydroxypropionat...
ORGANISM(S): Metallosphaera sedula DSM 5348 
2013-03-05 | E-GEOD-39944 | biostudies-arrayexpress
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