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TranscriptomicsIdentification of global regulators of T-helper cell lineage specification (RNA-Seq)
The aim of the dataset was to identify genome-wide regulators of gene expression in early differentiation of human cord blood derived CD4+ T cells cultured under Th1 (Act+IL12) and Th2 (Act+IL4) polarizing conditions. Total RNA from naive CD4+ T cells was compared to total RNA from cells cultured in...
ORGANISM(S): Homo sapiens 
2015-11-20 | E-GEOD-71645 | biostudies-arrayexpress
UnknownThe Relationship Between Marijuana and Conventional Cigarette Smoking Behavior from Early Adolescence to Adulthood.
Not available
S-EPMC5505066 | biostudies-literature
TranscriptomicsIdentification of global regulators of T-helper cell lineage specification (BeadChip)
The aim of the dataset was to identify genome-wide regulators of gene expression in early differentiation of human cord blood derived CD4+ T cells cultured under Th1 (Act+IL12) and Th2 (Act+IL4) polarising conditions. Total RNA from naive CD4+ T cells was compared to total RNA from cells cultured in...
ORGANISM(S): Homo sapiens 
2015-11-20 | E-GEOD-71575 | biostudies-arrayexpress
GenomicsGenome-wide detection of STAT6 binding sites in IL-4 treated naive human CD4+ T cells
STAT6 is a major transcription factor driving the polarization of Th2 cells in response to IL-4. STAT6 is phosphorylated by Jak1 and Jak3 kinases at the IL-4 receptor, after which phosphorylated STAT6 forms a homodimer and translocates into the nucleus. There STAT6 binds to specific DNA sequences, r...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-17850 | biostudies-arrayexpress
TranscriptomicsSystematic evaluation of variability in simulated ChIP-chip experiments
The most widely-used method for detecting and measuring genome-wide protein-DNA interactions is chromatin immunoprecipitation on tiling microarrays, commonly known as ChIP-chip. Many tiling array platforms, amplification methods, and analysis algorithms exist for ChIP-chip, but a rigorous assessment...
ORGANISM(S): Homo sapiens 
2008-01-31 | E-GEOD-9842 | biostudies-arrayexpress
UnknownResults of the two incidence screenings in the National Lung Screening Trial.
Not available
S-EPMC4307922 | biostudies-literature
TranscriptomicsSubgroup specific somatic copy number aberrations in the medulloblastoma genome [mRNA]
Affymetrix Human Gene 1.1 ST Array profiling of 285 primary medulloblastoma samples. Total RNA was extracted from primary medulloblastoma samples and hybridized to Affymetrix Human Gene 1.1 ST Arrays (24-Array Plates) according to the manufacturer's instructions.
ORGANISM(S): Homo sapiens 
2012-07-26 | E-GEOD-37382 | biostudies-arrayexpress
TranscriptomicsSubgroup specific somatic copy number aberrations in the medulloblastoma genome [gDNA]
Affymetrix SNP6 profiling of 1087 medulloblastoma samples and 10 medulloblastoma cell lines. Genomic DNA was extracted from primary medulloblastoma samples and medulloblastoma cell lines and hybridized to Affymetrix SNP6 arrays according to the manufacturer's instructions.
ORGANISM(S): Homo sapiens 
2012-07-26 | E-GEOD-37384 | biostudies-arrayexpress
UnknownSubgroup-specific structural variation across 1,000 medulloblastoma genomes.
Not available
S-EPMC3683624 | biostudies-literature
UnknownThe major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
Not available
S-EPMC3235490 | biostudies-literature
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