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GenomicsA mesodermal factor, T (Brachyury), specifies mouse germ cell fate by directly activating germline determinants
Germ cells ensure reproduction and heredity in metazoans. Primordial germ cells (PGCs) in mice are induced in pluripotent epiblasts by BMP4 and WNT3, yet their mechanism of action remains unclear. Here, using in vitro PGC specification system, we show that WNT3 induces many transcription factors a...
ORGANISM(S): Mus musculus 
2013-12-11 | E-GEOD-50394 | biostudies-arrayexpress
TranscriptomicsA Mesodermal Factor, T (BRACHYURY), specifies mouse germ cell fate by directly activating germline determinants.
The germ cell lineage ensures reproduction and heredity in metazoans. Primordial germ cells (PGCs) in mice are induced in pluripotent epiblast cells by BMP4 and WNT3, yet their mechanism of action remains elusive. Here, using in vitro PGC specification system, we show that WNT3, but not BMP4, induce...
ORGANISM(S): Mus musculus 
2013-12-11 | E-GEOD-49689 | biostudies-arrayexpress
UnknownMultiple Gene Clusters and Their Role in the Degradation of Chlorophenoxyacetic Acids in Bradyrhizobium sp. RD5-C2 Isolated from Non-Contaminated Soil.
Not available
S-EPMC8446748 | biostudies-literature
TranscriptomicsGene expression microarray analysis on the medial prefrontal cortex of Schnurri-2 knockout and wild-type control mice
Schnurri-2 (Shn-2), an NF-kappa B site-binding protein, tightly binds to the enhancers of major histocompatibility complex (MHC) class I genes and inflammatory cytokines, which have been shown to harbor common variant single nucleotide polymorphisms associated with schizophrenia. Shn-2 knockout mice...
ORGANISM(S): Mus musculus 
2013-08-13 | E-GEOD-42775 | biostudies-arrayexpress
TranscriptomicsGene expression microarray analysis on hippocampus of Schnurri-2 knockout and wild-type control mice
Schnurri-2 (Shn-2), an NF-kappa B site-binding protein, tightly binds to the enhancers of major histocompatibility complex (MHC) class I genes and inflammatory cytokines, which have been shown to harbor common variant single nucleotide polymorphisms associated with schizophrenia. Shn-2 knockout mice...
ORGANISM(S): Mus musculus 
2013-08-13 | E-GEOD-41307 | biostudies-arrayexpress
TranscriptomicsGene expression microarray analysis on the dentate gyrus of Schnurri-2 knockout and wild-type control mice
Schnurri-2 (Shn-2), an NF-kappa B site-binding protein, tightly binds to the enhancers of major histocompatibility complex (MHC) class I genes and inflammatory cytokines, which have been shown to harbor common variant single nucleotide polymorphisms associated with schizophrenia. Shn-2 knockout mice...
ORGANISM(S): Mus musculus 
2013-08-13 | E-GEOD-42777 | biostudies-arrayexpress
UnknownInterferon-alpha modulates the chemosensitivity of CD133-expressing pancreatic cancer cells to gemcitabine.
Not available
S-EPMC7659312 | biostudies-literature
UnknownGranzyme B Expression in the Tumor Microenvironment as a Prognostic Biomarker for Patients with Triple-Negative Breast Cancer.
Not available
S-EPMC10526301 | biostudies-literature
UnknownSerum monocyte fraction of white blood cells is increased in patients with high Gleason score prostate cancer.
Not available
S-EPMC5471051 | biostudies-literature
UnknownCharacterization of Brain Volume Changes in Aging Individuals With Normal Cognition Using Serial Magnetic Resonance Imaging.
Not available
S-EPMC10308250 | biostudies-literature
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