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MetabolomicsGrowth control of the eukaryote cell: a systems biology study in yeast
Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rate) on the transcriptome, proteome, endometabolome and exometabolome of the yeast Saccharomyces cerevisiae. Each function...
2012-04-19 | MTBLS8 | MetaboLights
TranscriptomicsHuman lung adenocarcinoma DNA methylation profiling by MSNP
Lung adenocarcinoma’s genomic alterations exhibit vast variation. Lung adenocarcinoma also has previously described intrinsic gene expression subtypes (Hayes et al. 2006, PMID: 17075127). This study detect global methylation differences among gene expression subtypes. These specimens were also assay...
ORGANISM(S): Homo sapiens 
2012-05-16 | E-GEOD-36438 | biostudies-arrayexpress
TranscriptomicsHuman lung adenocarcinoma DNA copy number profiling
Lung adenocarcinoma’s genomic alterations exhibit vast variation. Lung adenocarcinoma also has previously described intrinsic gene expression subtypes (Hayes et al. 2006, PMID: 17075127). This study’s aim was to detect and validate subtype-specific alterations. A portion of these specimens were a...
ORGANISM(S): Homo sapiens 
2012-05-16 | E-GEOD-36363 | biostudies-arrayexpress
TranscriptomicsHif1α down-regulation is associated with transposition of great arteries in mice treated with a RA antagonist
Aims: Congenital heart defect (CHD) account for 25% of all human congenital abnormalities. Very few CHD-causing genes have been identified so far; so, to discover further genes we performed a global transcriptome analysis in mouse models of CHD. Methods and results: By the use of a retinoic acid com...
ORGANISM(S): Mus musculus 
2010-09-20 | E-GEOD-19012 | biostudies-arrayexpress
UnknownEarly Antibiotic Administration Is Associated with a Reduced Infection Risk When Combined with Primary Wound Closure in Patients with Open Tibia Fractures.
Not available
S-EPMC7899592 | biostudies-literature
UnknownHayes Yard virus: a novel ephemerovirus isolated from a bull with severe clinical signs of bovine ephemeral fever is most closely related to Puchong virus.
Not available
S-EPMC7191811 | biostudies-literature
UnknownCOMT Val158Met polymorphism moderates the association between PTSD symptom severity and hippocampal volume.
Not available
S-EPMC5373706 | biostudies-literature
GenomicsFOXK2 ChIP-seq
Chromatin immunoprecipitation of FOXK2 (tagged with Flag and His tags) in U2OS cells detected by SOLiD sequencing. ***Correction March 2014: The sample “FOXK2_Dox_treated” has been renamed, it was originally named “FOXK2_rep2”. A new sample “FOXK2_rep2” has been added, with new files. It has come to...
ORGANISM(S): Homo sapiens 
2011-01-20 | E-MTAB-565 | biostudies-arrayexpress
UnknownAssociation of Antifolate Response Signature Status and Clinical Activity of Pemetrexed-Platinum Chemotherapy in Non-Small Cell Lung Cancer: The Piedmont Study.
Not available
S-EPMC10425722 | biostudies-literature
ProteomicsC9orf72 arginine-rich dipeptide repeat proteins disrupt importin beta-mediated nuclear import
Disruption of nucleocytoplasmic transport (NCT), including mislocalization of the importin beta cargo, TDP-43, is a hallmark of amyotrophic lateral sclerosis (ALS), including ALS caused by a hexanucleotide repeat expansion in C9orf72. However, the mechanism(s) remain unclear. Importin beta and its c...
ORGANISM(S): Homo sapiens (Human) 
2020-05-20 | PXD015656 | Pride
Importin beta Nuclear transport Amyotrophic lateral sclerosis C9orf72 
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