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To elucidate potential roles of piRNA in lung cancer, we analyzed global piRNA expression profiles in 8 NSCLC and 3 HBE cell lines. RNA-seq results showed that >99% of the approximately 4.5 million reads were between 26 and 32 bases. Most of the piRNA loci are represented by two or more identical re...
ORGANISM(S): Homo sapiens 
Hepatitis B virus (HBV) uses e antigen (HBe) which is dispensable for virus infectivity to modulate host immune responses and to achieve viral persistence in human hepatocytes. The HBe precursor (p25) is directed to the endoplasmic reticulum (ER), where cleavage of the signal peptide (sp) gives rise...
ORGANISM(S): Homo sapiens (Human) Hepatitis B virus 
2022-07-01 | PXD025430 | Pride
Comparison between the effects of progesterone (P4) and medroxyprogesterone acetate (MPA) combined to estradiol (E2) on gene expression in normal breast cells to provide insight on their possible different impact on breast cancer risk in vivo. Total RNA obtained from cultures of normal human breast ...
ORGANISM(S): Homo sapiens 
We evaluated the profile of lncRNA and mRNA expression in control and 50μg/ml DEP treated HBE cells using the Arraystar Human LncRNA Array v3.0 array,7th generation. Our findings implicates that dysregulation of mitochondria invovled mRNAs may play important role in cytotoxicity of DEP. Examinati...
ORGANISM(S): Homo sapiens 
Effect of PM2.5 on circRNA expression of HBE cells
Effect of circDNA2 on gene expression of chronic PM2.5 exposed HBE cells
We performed translatome and transcriptome sequencing of A549, H1299 and HBE cells and analyzed the translation ratio (TR) of all genes Total RNA and ribosome-bound RNA were extracted from A549, H1299 and HBE cells, and the polyA+ mRNA was sequenced using Illumina GAIIx and HiSeq-2000. The reads wer...
ORGANISM(S): Homo sapiens 
MicroRNA microarray of HBE cell exposed to Al2O3 NPs, PM2.5, DEP
To identify the direct targets of circDNA2 in chronic PM2.5 exposed HBE cells, we performed RNA sequencing (RNA-seq) using RNA isolated from chronic PM2.5 exposed HBE cells or circDNA2 knockdown chronic PM2.5 exposed HBE cells (NC n=3 vs. KD n=3)
ORGANISM(S): Homo sapiens 
2025-04-17 | GSE283081 | GEO
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