Sort   by:  
 Page size 
TranscriptomicsMicro RNA expression from human hepatocellular carcinoma (HCC) specimens from patients undergoing liver transplantation.
Current selection criteria for liver transplant in patients with HCC (the Milan criteria) do not incorporate biologic metrics. MiRNA expression profiles correlate with HCC recurrence after transplant and can add significant value to the Milan criteria. MiRNA expression profiles were studied in HCC s...
ORGANISM(S): Homo sapiens 
2011-10-14 | E-GEOD-30297 | biostudies-arrayexpress
TranscriptomicsUnique MicroRNA Expression Signature Predicts Survival, Metastases and Recurrence of HCC
In this study we investigated the miRNA expression profile of Hepatocellular carcinoma (HCC) specimens from radical resection. We developed a unique 20 miRNA signature that could significantly distinguish HCC venous metastasis from metastasis-free HCC. In contrast to HCC staging systems, this signat...
ORGANISM(S): Homo sapiens 
2008-01-14 | E-GEOD-6857 | biostudies-arrayexpress
TranscriptomicsMicroRNA Profile Predicts Recurrence of Hepatocellular Carcinoma in Milan Criteria Cases with Mild Liver Cirrhosis.
In this study, we utilized microRNA expression profiling to assess risk of HCC recurrence after liver resection. We examined microRNA expression profiling in paired tumor and non-tumor liver tissues of 73 HCC patients with mild cirrhosis (Child-Pugh A/B) who satisfy Milan Criteria. We constructed pr...
ORGANISM(S): Homo sapiens 
2011-02-08 | E-GEOD-21362 | biostudies-arrayexpress
ProteomicsProteomic signatures in distant normal tissues demonstrate superior predictive value for hepatocellular carcinoma recurrence
To investigate the molecular signatures associated with hepatocellular carcinoma (HCC) recurrence, we conducted a comprehensive proteomic analysis using clinical samples, including adjacent normal tissues (ANTs), primary tumor tissues (PTTs), and distant normal tissues (DNTs) (n=8 per group). These ...
ORGANISM(S): Homo sapiens (Human) 
2025-11-25 | PXD065775 | Pride
Human Hcc recurrence Liver 
TranscriptomicsA possible role of miRNAs as predictive markers for the recurrence of hepatocellular carcinoma after liver transplantation
Background and aims: Liver transplantation (LT) is the most radical treatment for hepatocellular carcinoma (HCC) with high rates of long-term survival, but tumor recurrence after LT is an unresolved problem. The aim of our study was to identify predictive markers for tumor recurrence after liver tra...
ORGANISM(S): Homo sapiens 
2016-03-01 | E-GEOD-64989 | biostudies-arrayexpress
TranscriptomicsCombining Clinical, Pathology, and Gene Expression Data to Predict Recurrence of Hepatocellular Carcinoma
Background: Hepatocellular carcinoma (HCC) is among the top-five cancer killers worldwide. Here, we describe our analysis of 20 gene signatures with reported prognostic value in a cohort of patients with early stage HCC treated with surgical resection. Methods: We performed gene-expression profiling...
ORGANISM(S): Homo sapiens 
2011-02-17 | E-GEOD-20140 | biostudies-arrayexpress
ProteomicsCombined Protein Signature of ALDH1A1, LGALS3, LGALS3BP Predicts Cancer Recurrence Post-Liver Transplantation Beyond Milan Hepatocellular Carcinoma
Background: Liver transplantation (LT) for Hepatocellular carcinoma (HCC) can be offered to patients beyond Milan criteria. However, there are currently no molecular markers that can be used on HCC explant histology to predict recurrence, which arises in up to 20% of LT recipients. The goal of our s...
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD022881 | Pride
Hepatocellular carcinoma Proteomics Recurrence Liver Galectin 
TranscriptomicsAffymetrix SNP array data for hepatocellular carcinoma tissue
Genetic variations play an important role in tumor development and metastasis. Hepatocellular carcinoma (HCC) is one of leading cause of cancer-related death. Despite improvements in surveillance and clinical treatment strategies, the prognosis of HCC remains dismal. Affymetrix SNP 6.0 array were us...
ORGANISM(S): Homo sapiens 
2012-10-26 | E-GEOD-29667 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human liver cancer samples
The identification of HCC patients with different risks of recurrence by incorporating the status of clinicopathological features available at diagnosis and gene expression profiling associated with recurrence
ORGANISM(S): Homo sapiens 
2007-11-12 | E-TABM-292 | biostudies-arrayexpress
TranscriptomicsIdentification of cholangiocarcinoma-like gene expression traits in hepatocellular carcinoma
We performed gene expression profiling of hepatocellular carcinoma (HCC), cholangiocarcinoma (CC), and mixed type of combined HCC and CC (CHC). In comparison of the profiles, a novel class of HCC expressing CC-like traits was identified. Gene expression profiling of 70 hepatocellular carcinoma (HCC)...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-15765 | biostudies-arrayexpress
Sort   by:  
 Page size