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MetabolomicsScreening of Differential Metabolites and Metabolic Pathway Analysis Related to Colorectal Adenoma Recurrence

Background To analyze the differences in gut metabolites between the CRA (colorectal adenoma) recurrence and non-recurrence groups, to identify characteristic metabolites and related metabolic pathways associated with recurrence, and to provide new evidence for risk stratification and interv...

2026-08-08 | MTBLS15298 | MetaboLights
MetabolomicsSerum metabolomic profiles identify ER-positive early breast cancer patients at increased risk of disease recurrence in a multicentre population

PURPOSE: Detecting signals of micrometastatic disease in early breast cancer (EBC) patients could improve risk stratification and allow better tailoring of adjuvant therapies. We have previously shown that postoperative serum metabolomic profiles are predictive of relapse in a si...

2017-03-02 | MTBLS424 | MetaboLights
MetabolomicsMitochondrial Transplantation of Brown Adipocytes Interferes with the Metabolism of Tumor Stem Cells and Inhibits the Recurrence of Brain Glioma after Operation

Glioblastoma multiforme (GBM) is highly aggressive, with treatment resistance and recurrence driven by metabolically plastic glioma stem cells (GSCs). Inspired by brown adipose tissue (BAT) thermogenesis, researchers transplanted BAT-derived mitochondria (BA-Mito) into GSCs, reducing stemness mar...

2025-08-27 | MTBLS12901 | MetaboLights
TranscriptomicsMicroRNA profiling of human stage I non-small cell lung cancer to quantify microRNA changes associated with disease recurrence
Expression of 752 microRNAs in 77 cases of stage I non-small cell lung cancer was examined using a locked nucleic acid microarray to quantify microRNA changes associated with recurrence of the disease after surgical resection.
ORGANISM(S): Homo sapiens 
2010-04-07 | E-TABM-727 | biostudies-arrayexpress
ProteomicsProteomic signatures in distant normal tissues demonstrate superior predictive value for hepatocellular carcinoma recurrence
To investigate the molecular signatures associated with hepatocellular carcinoma (HCC) recurrence, we conducted a comprehensive proteomic analysis using clinical samples, including adjacent normal tissues (ANTs), primary tumor tissues (PTTs), and distant normal tissues (DNTs) (n=8 per group). These ...
ORGANISM(S): Homo sapiens (Human) 
2025-11-25 | PXD065775 | Pride
Human Hcc recurrence Liver 
ProteomicsHuman skull base chordoma LC-MSMS
The prognostic factors of skull base chordoma associated with outcomes of patients after surgical resection remain poorly defined. This project aimed to identify a novel prognostic factor for patients with skull base chordoma. Using a proteomics approach, we screened tumor biomarkersthat upregulated...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD025894 | Pride
Human Lc-msms Skull base chordoma 
TranscriptomicsA five-microRNA-signature predicting recurrence in HNSCC
The risk of locoregional or distant failure in advanced HPV-negative head and neck squamous cell carcinoma (HNSCC) patients is high. However, no suitable markers for stratification are clinically available. Thus, we aimed to identify a microRNA(miRNA)-signature predicting disease recurrence. For thi...
ORGANISM(S): Homo sapiens 
2018-09-06 | E-MTAB-5793 | biostudies-arrayexpress
MetabolomicsGut Microbiome and Metabolome Signatures in Calcium Oxalate Stone Recurrence: A Multi-Omics Study

Background: The incidence and recurrence rate of nephrolithiasis have been increasing annually. Recent evidence highlights a close association between the composition and function of the gut microbiome and the occurrence and recurrence of kidney stones. We performed a multi-omic study to investig...

2026-03-03 | MTBLS13960 | MetaboLights
TranscriptomicsMicroRNA Profile Predicts Recurrence of Hepatocellular Carcinoma in Milan Criteria Cases with Mild Liver Cirrhosis.
In this study, we utilized microRNA expression profiling to assess risk of HCC recurrence after liver resection. We examined microRNA expression profiling in paired tumor and non-tumor liver tissues of 73 HCC patients with mild cirrhosis (Child-Pugh A/B) who satisfy Milan Criteria. We constructed pr...
ORGANISM(S): Homo sapiens 
2011-02-08 | E-GEOD-21362 | biostudies-arrayexpress
TranscriptomicsIdentification and validation of a multigene predictor of recurrence in primary laryngeal cancer.
Background: Local recurrence is the major manifestation of treatment failure in patients with operable laryngeal carcinoma. Established clinicopathological factors cannot sufficiently predict patients that are likely to recur after treatment. Additional tools are therefore required to accurately ide...
ORGANISM(S): Homo sapiens 
2013-10-30 | E-GEOD-27020 | biostudies-arrayexpress
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