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GenomicsGenome-wide CRISPR-Cas9 screen in isogenic parental and RBM10-KO HCC827 cells
Genome-wide CRISPR-Cas9 knockout screen using TKOv1 sgRNA library performed in isogenic RBM10-proficient and RBM10-deficient HCC827 cells.
ORGANISM(S): Homo sapiens 
2024-03-01 | E-MTAB-13626 | biostudies-arrayexpress
GenomicsMutational analysis of HCC827 and HCC827-OR cell lines [HCC827OR_WES]
Mutational analysis of HCC827 and HCC827-OR cell lines [HCC827OR_WES]
PRJNA924700 | ENA
TranscriptomicsCharaterization of genetic alterations and gene expression signatures found in erlotinib-resistant and erlotinib/crizotinib dual-resistant HCC827 subpopulations
The non-small cell lung cancer (NSCLC) cell line HCC827 harbors an activating EGFR mutation (exon 19 deletion) that confers sensitivity to the FDA-approved EGFR inhibitor erlotinib. By applying the ClonTracer barcoding system, we were able to show the presence of pre-existing sub-populations in HCC8...
ORGANISM(S): Homo sapiens 
2014-10-07 | E-GEOD-62118 | biostudies-arrayexpress
GenomicsGene expression of HCC827 and HCC827-OR cell line [HCC827OR_RNA]
Gene expression of HCC827 and HCC827-OR cell line [HCC827OR_RNA]
PRJNA924692 | ENA
GenomicsGene expression of HCC827 and HCC827-TET2-KO cell line [HCC827_TET2_KO_RNA]
Gene expression of HCC827 and HCC827-TET2-KO cell line [HCC827_TET2_KO_RNA]
PRJNA923623 | ENA
GenomicsDistribution of genomic 5hmC marks in HCC827 and HCC827-TET2-KO cell line [HCC827_TET2_KO_5hmC]
Distribution of genomic 5hmC marks in HCC827 and HCC827-TET2-KO cell line [HCC827_TET2_KO_5hmC]
PRJNA923625 | ENA
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of HCC827 and HCC827/GR cells Transcriptomes
Next Generation Sequencing Facilitates Quantitative Analysis of HCC827 and HCC827/GR cells Transcriptomes
PRJNA820867 | ENA
GenomicsAnalysis of gene expression change between HCC827 SC and HCC827 shCEACAM6
Analysis of gene expression change between HCC827 SC and HCC827 shCEACAM6
PRJNA1220580 | ENA
ProteomicsEGFR-TKI-down-regulated proteins in HCC827 cells
EGFR mediates stabilities of a wide spectrum of proteins. Treatment of the cells with EGFR tyrosine kinase inhibitors (EGFR-TKIs) leads to degradation of these proteins. To define the proteins and corresponding pathways of EGFR-stabilized proteins, we use mass spectrum to quantify the protein level...
ORGANISM(S): Homo sapiens (Human) 
2025-05-13 | PXD050420 | Pride
Human egfr mutated lung cancer cells 
TranscriptomicsGene expression of HCC827 and HCC827-TET2-KO cell line [HCC827_TET2_KO_RNA]
To investigate the influence of TET2 knock-down in lung cancer cell line, We performed gene expression profiling analysis using data obtained from RNA-seq of HCC827 cell line and HCC827-TET2-KO cell line.
ORGANISM(S): Homo sapiens 
2024-03-13 | GSE222829 | GEO
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