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Inflammatory signals must be regulated and kept in check in order to prevent tissue damage.  This is especially true in the cornea, where damage can induce loss of transparency, essential for vision.  Toll-like receptors (TLRs) are present at the ocular surface and, in addition to being protective...
ORGANISM(S): Homo sapiens 
Transcriptomic analysis of APC knock down HCEC 1CT cells compared to the wild type HCEC 1CT cells.
Transcriptomic analysis of APC knock down HCEC 1CT cells compared to the wild type HCEC 1CT cells.
We performed RNA sequencing analysis of two human colon epithelial cell lines (HCEC 1CT_WT and HCEC 1CT_APC KD).
ORGANISM(S): Homo sapiens 
2020-09-25 | GSE152562 | GEO
Human corneal endothelial cells (HCEC) form a monolayer by adhering tightly through their intercellular adhesion molecules. Located at the posterior corneal surface, they maintain corneal translucency by dehydrating the corneal stroma, mainly through the Na+- and K+-dependent ATPase (Na+/K+-ATPase)....
ORGANISM(S): Homo sapiens 
Transcriptome of 3D cultivated colon cancer cell lines (HCT116, SW620, DLD1) and HCEC-1CT
APC knock down HCEC 1CT cells compared to the wild type HCEC 1CT cells
In order to investigate sophisticated events during cancer initiation, we established early colorectal cancer development model. We performed scRNA-seq and analyzed the scRNA-seq dataset. scRNA-seq was conducted at 3- and 7-days after transduction of shRNA targeting APC (shAPC) and scrambled shRNA (...
ORGANISM(S): Homo sapiens 
2020-09-25 | GSE152745 | GEO
Inflammatory signals must be regulated and kept in check in order to prevent tissue damage. This is especially true in the cornea, where damage can induce loss of transparency, essential for vision. Toll-like receptors (TLRs) are present at the ocular surface and, in addition to being protective a...
ORGANISM(S): Homo sapiens 
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