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Indole is a bacterial signal secreted by pathogenic and commensal Escherichia coli in the stationary phase at high concentrations (~600 µM). Prior work from our lab has shown that indole decreases E. coli O157:H7 (EHEC) chemotaxis, motility, attachment to epithelial cells and biofilm formation. How...
ORGANISM(S): Homo sapiens 
Comparison of wild type S. flexneri 2457T gene expression to deletion mutant of S. flexneri 2457T gene S4473 at three growth phases and intracellularly Broth culture was grown to mid-log in LB, intracellular growth was 3 hours post invasion of HCT-8 cell (colonic epithelial cell line).
ORGANISM(S): Shigella flexneri 2a str. 2457T 
Expression profiles of circRNA in HCT-8 cells infected with Cryptosporidium parvum IId subtype
Expression data from Control or TRIB3-silenced HCT-8 cells
RNA-Seq analysis of HCT-8 cells infected with BCoV and/or Cparvum
We selected and characterized doxorubicin/5FU resistant HCT-8/R clones from sensitive parental cells, analyzing several parameters: cell cycle phase distribution, apoptotic activity, expression, distribution and functionality of the P-gp efflux pump, ultrastructural features, invasiveness and transc...
ORGANISM(S): Homo sapiens 
Transcriptomics of human adenocarcinoma cell line HCT-8 infected with Cryptosporidium parvum treated with indole
Expression profiles of mRNA and lncRNA in HCT-8 cells infected with Cryptosporidium parvum IId subtype
Cryptosporidium parvum is one of the most important opportunistic enteric parasites, causing severe diarrhea in immunocomprised human and animals. However, few effective control agents were available for this parasite. circular RNA (circRNA) was discovered to play key roles in many diseases, and the...
ORGANISM(S): Homo sapiens 
2022-12-15 | GSE162990 | GEO
Complete growth medium RPMI-1640 which contains 10% FCS, 1% Penicillin-Streptomycin Solution was used for cell culture. Both cell lines were maintained at 37 °C in a humidified atmosphere containing 5% CO2. MTT assay was performed to determine the 5 ‑ FU resistance in both of HCT-8/WT and HCT-8/5-FU...
ORGANISM(S): Homo sapiens 
2017-03-15 | GSE81006 | GEO
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