Hdx mass spectrometry

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Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom (2)
Chloé Martens, Ph.D Chercheuse Qualifiée - FRS.FNRS Group Leader Structure and Function of Biological Membranes - Chemistry Department chloemartenslab.com - sfmb.ulb.be Phone :+32 2 650 53 83 Université Libre de Bruxelles - Campus Plaine. Building BC, Room 1C4 110 - Boulevard du Triomphe, Accès 2 1050 Brussels - Belgium (2)
Department of Chemistry, King’s College London, SE1 1DB, London, UK Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, M13 9PT, Manchester, UK Manchester Institute of Biotechnology, The University of Manchester, M1 7DN, Manchester, UK (2)
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Institute of Microbiology,The Czech Academy of Sciences (2)
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Epitope Mapping of Human Polyclonal Antibodies to the fHbp Antigen of a Neisseria Meningitidis Vaccine by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) - part 2

Antigen-antibody interactions play a key role in the immune response post vaccination and the mechanism of action of antibody-based biopharmaceuticals. 4CMenB is a multicomponent vaccine against Neisseria meningitidis serogroup B in which factor H binding protein (fHbp) is one of the key antigens. I...

ORGANISM(S): Homo sapiens (Human)

2024-05-22 | PXD047712 | Pride

Epitope Mapping of Human Polyclonal Antibodies to the fHbp Antigen of a Neisseria Meningitidis Vaccine by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)

ORGANISM(S): Homo sapiens (Human)

2024-05-24 | PXD046572 | Pride

Polyclonal antibodies Pab Fhbp Hdx-ms

Online Hydrogen-Deuterium Exchange Traveling Wave Ion Mobility Mass Spectrometry (HDX-IM-MS): a Systematic Evaluation.

Not available

S-EPMC5438439 | biostudies-literature

Quantitative Evaluation of Native Protein Folds and Assemblies by Hydrogen Deuterium Exchange Mass Spectrometry (HDX-MS).

Not available

S-EPMC6318237 | biostudies-literature

A structural model of the immune checkpoint CD160-HVEM complex derived from HDX-mass spectrometry and molecular modeling.

Not available

S-EPMC6355189 | biostudies-literature

Hybrid Mass Spectrometry Applied across the Production of Antibody Biotherapeutics.

Not available

S-EPMC11697328 | biostudies-literature

Hybrid Mass Spectrometry Approaches to Determine How L-Histidine Feedback Regulates the Enzyzme MtATP-Phosphoribosyltransferase.

Not available

S-EPMC5415358 | biostudies-literature

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.

Not available

S-EPMC6614034 | biostudies-literature

Hybrid mass spectrometry applied across the production of antibody biotherapeutics.

Post expression from the host cell, a bio-therapeutic will be subjected to several downstream processing steps prior to final formulation. Analysis of the product under various buffer conditions at each stage is desirable to show that the integrity of the sample is maintained and to monitor any pote...

ORGANISM(S): Homo sapiens (Human)

2024-07-12 | PXD051563 | Pride

Dynamics Purification stages Monoclonal antibody Hdx-ms Formulation Perfusion media

Hydrophilic Interaction Liquid Chromatography-Hydrogen/Deuterium Exchange-Mass Spectrometry (HILIC-HDX-MS) for Untargeted Metabolomics.

Not available

S-EPMC10932214 | biostudies-literature

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