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TranscriptomicsIdentification of a common prognostic gene signature and its association with miR-181 regulation in human acute myeloid leukemia
This SuperSeries is composed of the following subset Series: GSE30258: Identification of miR-181 target genes and a common prognostic gene signature in AML GSE30285: Identification of prognostic gene signatures in AML Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30257 | biostudies-arrayexpress
TranscriptomicsAffymetrix Human Exon 1.0 ST array assay of 15 human MLL-associated samples and 9 human normal bone marrow [HuEx-1_0-st]
To identify potential target genes of leukemia-related miRNAs such as miR-196b and miR-150 in human MLL-associated leukemia, we performed Affymetrix Human Exon 1.0 ST array assay of 15 human MLL-associated samples and 9 human normal bone marrow (including 3 each of CD34+, CD33+, and MNC) cell sample...
ORGANISM(S): Homo sapiens 
2012-08-09 | E-GEOD-34184 | biostudies-arrayexpress
TranscriptomicsTranscriptome sequencing of human fetal heart
We sequenced 2 heart samples from human fetal donors and detected the differential expressed mRNAs and lncRNAs. The network of significant differential expressed transcripts could be associated to developmental program. examination mRNA and lncRNA expression in heart tissues
ORGANISM(S): Homo sapiens 
2016-02-10 | E-GEOD-68279 | biostudies-arrayexpress
TranscriptomicsAffymetrix gene arrays of leukemic BM samples from 24 mice including 9 primary
To identify such targets of leukemia-related miRNAs such as miR-196b, we conducted Affymetrix gene arrays of leukemic BM samples from 24 mice including 9 primary (including 3 each of negative control, MLL-AF9, and miR-196b+MLL-AF9) and 15 secondary (including 3 negative control, 6 MLL-AF9, and 6 miR...
ORGANISM(S): Mus musculus 
2012-08-09 | E-GEOD-34185 | biostudies-arrayexpress
Transcriptomics26 mouse embryonic stem cell , embryonic body cell, and colony-forming samples (affymetrix exon array)
Intragenic microRNAs (miRNAs), including both intronic and exonic miRNAs, accounting approximately 50% of total mammalian miRNAs. Previous studies showed that intragenic miRNAs are often co-expressed with their host genes, and thus it was believed that intragenic miRNAs and their host genes are deri...
ORGANISM(S): Mus musculus 
2011-03-02 | E-GEOD-27397 | biostudies-arrayexpress
Transcriptomics81 human leukemia samples (affymetrix exon array)
Intragenic microRNAs (miRNAs), including both intronic and exonic miRNAs, accounting approximately 50% of total mammalian miRNAs. Previous studies showed that intragenic miRNAs are often co-expressed with their host genes, and thus it was believed that intragenic miRNAs and their host genes are deri...
ORGANISM(S): Homo sapiens 
2011-03-02 | E-GEOD-27370 | biostudies-arrayexpress
UnknownIdentification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study.
Not available
S-EPMC3595425 | biostudies-literature
TranscriptomicsIdentification of prognostic gene signatures in AML
Increased expression levels of miR-181 family members have been shown to be associated with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here we show that increased expression of miR-181a and miR-181b is also significantly (P < .05; Cox regression) associated wit...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30285 | biostudies-arrayexpress
TranscriptomicsIdentification of miR-181 target genes and a common prognostic gene signature in AML
Increased expression levels of miR-181 family members have been shown to be associated with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here we show that increased expression of miR-181a and miR-181b is also significantly (P < .05; Cox regression) associated wit...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30258 | biostudies-arrayexpress
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