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ProteomicsProteomic study of hepatic encephalopathy model induced by thioacetamide in mice
200mg/kg thioacetamide was injected every day for three times to form a mold. The proteomic results of brain tissue in this model were analyzed.
ORGANISM(S): Rattus Rattus 
2023-06-20 | PXD043126 |
TranscriptomicsTranscriptomic Assay of CD8 2012-05-15
In this study, Genome-wide transcriptomes of CD8+ T cells from HCV/HIV co-infected or mono-infected treatment-naive individuals were analyzed by using microarray assays. Pairwise comparisons were performed and differentially expressed genes were identified followed by quantitative real time PCR (qRT...
ORGANISM(S): Homo sapiens 
2012-05-17 | E-MEXP-3635 | biostudies-arrayexpress
TranscriptomicsDeletion of Pten leads to liver steatosis and tumor formation
We found that deleting Pten in Albumin expressing cells results in liver steatosis as early as 1 month of age. The mice develop hyperplasia and tumor phenotypes starting at 7-8 months of age. At 12 months and beyond, all mice develope spontanous liver tumors of mixed lineage phenotypes dihydrocol...
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-70681 | biostudies-arrayexpress
TranscriptomicsExpansion of hepatic tumor progenito cell population in PTEN deficient mice requires liver injury and is reversed by deletion of Akt2
We found that hepatic injury induced by PTEN loss establishes a selection pressure for tumorinitiating cells (TICs) to proliferate and form mixed lineage tumors. The Pten null mice demonstrate escalating levels of hepatic injury prior to proliferation of hepatic progenitors. Attenuation of hepatic i...
ORGANISM(S): Mus musculus 
2016-03-31 | E-GEOD-70501 | biostudies-arrayexpress
Transcriptomicssmall RNA deep-sequencing of mature sperm, testis and uterus in mice
In order to discover novel small RNAs expressed in mature sperm, we isolated mature sperm from mouse cauda epididymis, comparing with data from adult tesis and uterus. The small RNA fraction (18-40nt) was cloned and sequenced from total RNA of mature sperm, testis and uterus of mice. RNAs extracted ...
ORGANISM(S): Mus musculus 
2013-01-31 | E-GEOD-38702 | biostudies-arrayexpress
TranscriptomicsSmall non-coding RNA expression in mouse elongated spermatids
In order to discover novel small RNAs expressed in elongated spermatids, we isolated elongated spermatids from mouse testis. The small RNA fraction (18-40nt) was cloned and sequenced from total RNA. RNAs extracted from elongated spermatids were used for high throughput sequencing analysis
ORGANISM(S): Mus musculus 
2013-01-31 | E-GEOD-40397 | biostudies-arrayexpress
GenomicsEGAD00000000054
NCI-H209 is an immortal cell line derived from a bone marrow metastasis of a patient with small cell lung cancer, taken before chemotherapy. The specimen showed histologically typical small cells with classic neuroendocrine features. NCI-BL209 is an EBV-transformed B-cell line derived from the same ...
EGAD00000000054 | EGA
GenomicsA small cell lung cancer genome reports complex tobacco exposure signatures
Cancer is driven by mutation. Worldwide, tobacco smoking is the major lifestyle exposure that causes cancer, exerting carcinogenicity through 60 chemicals that bind and mutate DNA. Using massively parallel sequencing technology, we sequenced a small cell lung cancer cell line, NCI-H209, to explore t...
EGAS00000000051 | EGA
TranscriptomicsDynamic nature of epigenetic patterns observed during the Mars 520-d mission simulation
Interplanetary human spaceflight represents a formidable medical challenge, but also provides a unique platform for investigating human adaptation to extreme environmental changes. Understanding the long-term effects of isolation has relevance in a range of scenarios and it is well recognized that a...
ORGANISM(S): Homo sapiens 
2015-01-14 | E-GEOD-64950 | biostudies-arrayexpress
UnknownEfficacy and Safety of Ginkgo Diterpene Lactone Meglumine in Acute Ischemic Stroke: A Randomized Clinical Trial.
Not available
S-EPMC10425831 | biostudies-literature
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