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TranscriptomicsTranscription factor SOX17 overexpression in hematopoietic stem cells
This SuperSeries is composed of the following subset Series: GSE30444: Retroviral Sox17 over-expression adult hematopoietic stem/progenitor cells microarray GSE30445: Sox17-transgenic hematopoietic stem cell microarray Refer to individual Series
ORGANISM(S): Mus musculus 
2011-07-14 | E-GEOD-30446 | biostudies-arrayexpress
TranscriptomicsSox17-transgenic hematopoietic stem cell microarray
The transcription factor SOX17 is expressed by fetal, but not adult hematoipoietic stem cells (HSCs), and is required for the maintenance of fetal and neonatal, but not adult, HSCs. In the current study we show that ectopic expression of Sox17 in adult HSCs and transiently reconstituting multipotent...
ORGANISM(S): Mus musculus 
2011-07-14 | E-GEOD-30445 | biostudies-arrayexpress
TranscriptomicsRetroviral Sox17 over-expression adult hematopoietic stem/progenitor cells microarray
The transcription factor SOX17 is expressed by fetal, but not adult hematoipoietic stem cells (HSCs), and is required for the maintenance of fetal and neonatal, but not adult, HSCs. In the current study we show that ectopic expression of Sox17 in adult HSCs and transiently reconstituting multipotent...
ORGANISM(S): Mus musculus 
2011-07-14 | E-GEOD-30444 | biostudies-arrayexpress
ProteomicsSynthetic lethal combinations targeting PLK1-CBX8-GPX4 axis with BRAF and EGFR inhibition in BRAF V600E colorectal cancer
Metastatic BRAFV600E colorectal cancer (CRC) confers poor prognosis and run into a bottleneck in the current treatment strategies. To identify regulatory pathways independent of the MAPK pathway in BRAFV600E CRC, we performed CRISPR-Cas9 screening, and and find targeting glutathione peroxidase 4 (GP...
ORGANISM(S): Homo Sapiens 
2024-11-25 | PXD058213 |
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