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TranscriptomicsTranscription profiling of zebrafish ZF4 and PAC2 cell lines cultured in medium with or without FCS
In this study, zebrafish ZF4 and PAC2 cells were seeded in 0.5% or 1% FCS, respectively, and grown to 85% confluence and subsequently cultured for 24 hours without serum. Then they were treated with either medium without serum or medium with serum (ZF4 in 10% FCS and PAC2 in 15% FCS).After 6 hours, ...
ORGANISM(S): Danio rerio 
2006-06-12 | E-MEXP-736 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of two 24 hour old zebrafish embryos from the Tuebingen line
Transcriptome analyses of 24-hour zebrafish embryos from the Tuebingen line were performed using the Affymetrix GeneChip Zebrafish Genome Array (GeneChip 430)
ORGANISM(S): Danio rerio 
2006-06-12 | E-MEXP-737 | biostudies-arrayexpress
Transcriptomicszebrafish liver tumor signatures
transcriptome profiling of zebrafish liver tumors comparing with healthy liver tissues Zebrafish liver tumors were induced by exposure to 7,12-dimethylbenz(α)anthracene (DMBA). 5 zebrafish liver tumors and 6 healthy zebrafish livers were used to detect gene signatures in zebrafish liver tumors. A mi...
ORGANISM(S): Danio rerio 
2011-07-07 | E-GEOD-29307 | biostudies-arrayexpress
TranscriptomicsRaf/MEK signatures in zebrafish liver cells
An inducible oncogenic cell line ZFL-?Raf1-ER was established, in which oncogenic human Raf-1(?Raf1) can be activated in zebrafish liver cells by administration of 4-hydroxytamoxifen (4HT). Transcriptional profilling of the ZFL-?Raf1-ER cells with and without administration of 4HT and/or the MEK inh...
ORGANISM(S): Danio rerio 
2011-07-07 | E-GEOD-29308 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of ERK1 and ERK2 knockdown in zebrafish embryos at blastula stage
ERK1 and ERK2 MAPKs are intensively studied signaling proteins that are involved in numerous cellular processes and signaling networks. However, their specific functions in embryonic development remain elusive. The upstream activation pathways for ERK1 and ERK2 are considered to be highly similar, a...
ORGANISM(S): Danio rerio 
2008-01-01 | E-MEXP-1163 | biostudies-arrayexpress
TranscriptomicsDepletion of beta1 integrins in triple negative breast cancer cells causes extensive alterations in gene expression profiles
Interactions with the extracellular matrix (ECM) through integrin adhesion receptors provide cancer cells with physical and chemical cues that act in concert with growth factors to support survival and proliferation. Preclinical studies testing beta1 integrin antagonists in (breast) cancer models h...
ORGANISM(S): Mus musculus 
2014-02-11 | E-MTAB-2185 | biostudies-arrayexpress
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