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ProteomicsTengdan Capsule Prevents Hypertensive Kidney Damage in SHR by Inhibiting Periostin-mediated Renal Fibrosis
In order to reveal the potential molecular mechanism of TDC in renal protection of rats with essential hypertension, TMT-based quantitative proteomics analysis method was used to conduct quantitative analysis of proteins extracted from kidney of SHR of model and TDC treatment groups after 4 weeks of...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-10 | PXD024102 | Pride
Teng dan capsule  hypertension-induced kidney damage  periostin  tgfβ/smad signaling pathway  inflammatory response  human kidney hek293 cells 
UnknownGenetic Factors Underlying Single Fiber Quality in A-Genome Donor Asian Cotton (Gossypium arboreum).
Not available
S-EPMC8689003 | biostudies-literature
ProteomicsThe deubiquitinase USP13 maintains cancer cell stemness by promoting FASN stability in small cell lung cancer
USP13 is significantly amplified in over 20% of lung cancer patients and critical for tumor progression. However, the functional role of USP13 in small cell lung cancer (SCLC) remains largely unclear. In this study, we found that the deubiquitinase USP13 is highly expressed in SCLC tumor samples and...
ORGANISM(S): Homo Sapiens 
2022-04-06 | PXD032993 |
ProteomicsFunctional identification of protocadherin alpha 9 (PCDHA9) as a candidate causative gene for amyotrophic lateral sclerosis
Mice were sacrificed after anesthesia by isoflurane following neck cutting. The spinal cord L3-L5 was taken and frozen in liquid nitrogen immediately and the ventral horn of the bilateral spinal cord (about 400um thick in gray matter area) was collected at low temperature. The samples were digested ...
ORGANISM(S): Mus Musculus 
2023-06-12 | PXD042929 |
ProteomicsExplore the proteomics characteristics of urine and serum from COVID-19 patients
we obtained the proteome profiling of serum and urine specimen collected from 50 COVID-19 patients and 40 healthy subjects. We then used TMT-labeled proteomics and quantified 1,494 and 3,854 proteins in serum and urine, respectively. We then explored the pathogenic characteristics in body fluids aft...
ORGANISM(S): Homo Sapiens 
2021-12-30 | PXD030662 |
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