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ProteomicsTargeting LRBA triggers CTLA4 degradation and antitumor immunity for cancer immunotherapy
The lipopolysaccharide-responsive beige-like anchor protein (LRBA) deficiency causes severe autoimmune diseases and cytotoxic T-lymphocyte-associated protein 4 (CTLA4) loss in humans. However, the impact of LRBA on antitumor immunity remains understudied. Here, we identified the role of LRBA in anti...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-23 | PXD064363 | Pride
ProteomicsAP-MS Raw data of C. burnetii-host PPIs
Fifty-three Coxiella effectors were expressed in HEK-293T cells, and the Strep-tagged Coxiella effectors and the corresponding interacting complex were purified for MS analysis. The LC-MS/MS analyses were performed with an Orbitrap Fusion Tribrid mass spectrometer (Thermo Fisher Scientific) coupled ...
ORGANISM(S): Homo Sapiens 
2022-03-18 | PXD032380 |
ProteomicsProteomic study of SOAT1 protein targeting compounds in the treatment of liver cancer
Proteomic study of SOAT1 protein targeting compounds in the treatment of liver cancer
ORGANISM(S): Homo Sapiens 
2022-01-11 | PXD030873 |
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