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UnknownDeployment of cisplatin in Veterans with oropharyngeal cancer: toxicity and impact on oncologic outcomes.
Not available
S-EPMC10446265 | biostudies-literature
UnknownPembrolizumab for Platinum- and Cetuximab-Refractory Head and Neck Cancer: Results From a Single-Arm, Phase II Study.
Not available
S-EPMC5946724 | biostudies-literature
TranscriptomicsTranscriptome response of Methanobrevibacter ruminantium to lauric acid in cell culture.
Medium chain fatty acids (MCFA) have been shown to inhibit methanogenesis, disrupt the cell envelope, and decrease survival of Methanobrevibacter ruminantium M1 in a dose-, time-, and protonation level dependent way. However, the exact mechanisms behind these observations are still unknown. Althoug...
ORGANISM(S): Methanobrevibacter ruminantium 
2016-06-01 | E-GEOD-81199 | biostudies-arrayexpress
TranscriptomicsGene expression changes in femur bone induced by skeletal muscle unloading
Gene expression changes in femur bone induced by acute skeletal muscle unloading, which leads to physiological changes including muscle atrophy, weakness and results in bone remodelling and subsequent loss of bone mass, was investigated by hind-limb suspension (HLS) treatment of Male ICR mice (28–32...
ORGANISM(S): Mus musculus 
2010-12-21 | E-GEOD-11933 | biostudies-arrayexpress
TranscriptomicsDifferentiation of NUT midline carcinoma by epigenomic reprogramming
Knockdown of the oncogene, BRD4-NUT, in a rare cancer, termed NUTmidline carcinoma (NMC), results in morphologic features consistent with squamous differentiation. Treatment with the HDAC-inhibitor, TSA, appears to cause the same phenotype. Here, we use gene expression profiling to compare the cha...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-18668 | biostudies-arrayexpress
TranscriptomicsBiopsies from metastatic Clear Cell Renal Carcinoma before or after treatment with nivolumab
Tumor core needle biopsies from kidney or metastatic sites obtained at trial enrollment i.e. Screen and/or at Cycle 2 Day 8 (i.e.Week 4) from metastatic clear cell RCC patients treated with 0.2mpk, 3mpk or 10mpk (as 2nd or further line of therapy; Arms A,B,C) or 10mpk (as first line therapy; Arm D) ...
ORGANISM(S): Homo sapiens 
2016-05-15 | E-MTAB-3218 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling in 6-hydroxydopamine hemiparkinsonian rats reveals methamphetamine-mediated dopamine-independent changes in striatal gene expression.
Unilateral injections of 6-hydroxydopamine into the medial forebrain bundle (MFB) is used extensively as a model of Parkinson’s disease. The present experiments examined whether a single injection of methamphetamine (METH) (2.5 mg/kg) could still influence striatal gene expression after 6-hydroxydop...
ORGANISM(S): Rattus norvegicus 
2010-09-21 | E-GEOD-24233 | biostudies-arrayexpress
MetabolomicsMechanistic insights revealed by lipid profiling in monogenic insulin resistance syndromes (Mouse data)
Evidence from several recent metabolomic studies suggests that increased concentrations of triacylglycerols (TAGs) with shorter (14-16 carbon atoms), saturated fatty acids are associated with insulin resistance and the risk of type 2 diabetes. Although causality cannot be inferred from association s...
2017-03-02 | MTBLS327 | MetaboLights
TranscriptomicsTranscription profiling of Atlantic salmon following dietary substitution of fish oil with vegetable oils
There is an increasing drive to replace fish oil (FO) in finfish aquaculture diets with vegetable oils (VO), driven by the short supply of FO derived from wild fish stocks. Little is known of the consequences for fish health after such substitution. The effect of dietary VO on hepatic gene expressio...
ORGANISM(S): Salmo salar 
2008-10-27 | E-TABM-478 | biostudies-arrayexpress
ProteomicsPaenarthrobacter ilicis 6C glucose vs xanthan proteome
A novel Paenarthrobacter ilicis 6C isolate from soil found in Bielefeld, Germany, was sequenced and characterized by proteome analysis to provide the first clear look at a novel genus in the realm of xanthan degrading microorganisms. This research provides additional groundwork for the ongoing chara...
ORGANISM(S): Paenarthrobacter ilicis 
2025-06-13 | PXD063987 | Pride
Paenarthrobacter Proteomics Xanthan degradation Glucose metabolism Proteome 
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