Healthy ageing - OmicsDI

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Homo sapiens (140)
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Organisms

Homo sapiens (35)
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human gut metagenome (2)
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Repository

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Instrument Platform

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CHEBI ID

CHEBI:22660 (6)
CHEBI:25017 (6)
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CHEBI:32816 (6)
CHEBI:16027 (5)
CHEBI:16737 (5)
CHEBI:16919 (5)
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CHEBI:17002 (1)
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CHEBI:22868 (1)
CHEBI:61995 (1)

Metabolite Name

AMP (4)
Arginine (4)
Citrate (4)
Creatine (4)
Creatinine (4)
Fumarate (4)
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ADP (3)
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GDP (3)
GMP (3)
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Malate (3)
NADH (3)
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Tyrosine (3)
Xanthine (3)
1-Methylnicotinamide (2)
2-phosphoglycolate (2)
Acetoacetyl-CoA (2)

IsPrivate

False (2)

First Public Date

2025 (21)
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2022 (10)
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2018 (8)
2019 (6)
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2020 (4)
2016 (4)
2015 (4)
2014 (3)
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Modelling Approach

Ordinary differential equation model (2)

Study type

Transcription profiling by array (69)
Methylation profiling by array (15)
RNA-seq of coding RNA (15)
ChIP-chip by array (4)
Comparative genomic hybridization by array (3)
Methylation profiling by high throughput sequencing (3)
Human - Methylation microarray (2)
RNA-seq of non coding RNA (2)
Cell line - Methylation microarray (1)
Unknown experiment type (1)
Animal - One-color microarray (1)
Human - One-color microarray (1)
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Release Date

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2019 (219)
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2013 (63)
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2012 (40)
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2010 (31)
2008 (12)
2009 (8)
2007 (6)
2006 (1)
2003 (1)

Lab affiliation

State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei,China (2)
95 Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, 31077, France (1)
Affiliation: Division of Cell Matrix Biology & Regenerative Medicine, The University of Manchester [Data also submitted and owned by Dr Matiss Ozols (matiss.ozols@manchester.ac.uk)] (1)
Associate Professor, Institute of Advanced Study in Science and Technology (IASST), Guwahati-110035, Assam, India (1)
Center for Neuroscience and Cell Biology (1)
Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, 2052, Australia (1)
Centre of Biopharmaceutical Science for Healthy Ageing, Faculty of Pharmacy, Mahidol University, Bangkok, 10400, Thailand Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Bangkok, 10400, Thailand (1)
Centre of Biopharmaceutical Science for Healthy Ageing, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand (1)
Department of Analytical Biochemistry, Groningen Research Institute of Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands (1)
Department of Cell Biology, Harvard Medical School, Boston, MA (1)
Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charite ‐ Universitatsmedizin, Germany; German Center for Lung Research (DZL), Associated Partner Site, Germany; Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Germa (1)
Institut für Biochemie und Biophysik Friedrich-Schiller-Universität Hans-Knöll-Str. 2, D-07745 Jena (1)
Institute for Mitochondrial Diseases and Aging, Medical Faculty, University of Cologne, D-50931 Cologne, Germany, (1)
Institute of Genetics and Molecular Medicine, The University of Edinburgh, Western General Hospital, Crewe Road South, Edinburgh EH4 2XR, Scotland (1)
Institute of Healthy Ageing, UCL Department of Genetics, Evolution and Environment, London, WC1E 6BT (1)
J. Craig Venter Institute, Rockville, MD 20850 (1)
LBPC-PPC, Montpellier University, IRMB CHU Montpellier, INM INSERM, Montpellier, Occitanie, France (1)
Laboratory for Functional Genome Analysis LAFUGA, Gene Center, LMU München, Fedor-Lynen-Strasse 25, 81377 Munich, Germany (1)
Laboratory of Ageing and Pharmacology, Kolling Institute, The University of Sydney (1)
Leibniz Institute for Aging - Fritz-Lipmann-Institut (FLI) Beutenbergstraße 11 07745 Jena (1)
Leibniz Institute on Aging – Fritz Lipmann Institute (FLI), Beutenbergstrasse 11, 07745 Jena, Germany (1)
MRC Laboratory of Molecular Biology (1)
Max Planck Institute for Biology of Ageing, Cologne, Germany Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, London, UK (1)
Max Planck Institute for Biology of Ageing, Cologne, Germany. Institute of Healthy Ageing, and Department of Genetics, Evolution and Environment, UCL, London, UK. (1)
Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Str. 9b, D-50931 Cologne, Germany Institute of Healthy Ageing, Department of Genetics, Evolution and Environment,University College London, Darwin Building, Gower Street, London WC1E 6BT, UK (1)
National Clinical Research Center for Endocrine and Metabolic Diseases, Metabolic Syndrome Research Center, Department of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan, China (1)
RG Neurohomeostasis, Department of Psychiatry and Psychotherapy, University Hospital Bonn, Germany (1)
Roskamp Institute, Sarasota, Florida (1)
School of Biomedical Sciences, The University of Hong Kong (1)
School of Medical Sciences, Faculty of Medicine and Healthy, University of Sydney, Sydney, Australia. (1)

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1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

Neutrophil function declines with age, but little is known about the changes in neutrophil metabolism that take place in robust older people and older people with frailty. We used ¹H-NMR spectroscopy to investigate the metabolomic and lipidomic profiles of blood neutrophils from healthy y...

2026-03-26 | MTBLS6055 | MetaboLights

Targeting phospholipase PLAG-15 promotes healthy aging in C. elegans via lysosomal-related genes

Complex lipid metabolism plays a crucial role in regulating aging. We recently discovered that the phospholipid bis(monoacylglycero)phosphate (BMP) increases in aged human muscles and many mouse tissues. The phospholipase PLA2G15 is reportedly involved in BMP synthesis, however, its specific role in...

2025-06-19 | MTBLS12324 | MetaboLights

Glycerol 3-phosphate phosphatase/PGPH-2 counters metabolic stress and promotes healthy aging via a glycogen sensing-AMPK-HLH-30-autophagy axis in C. elegans

Metabolic stress caused by excess nutrients accelerates aging. We recently demonstrated that the newly discovered enzyme glycerol-3-phosphate phosphatase (G3PP; gene Pgp), which operates an evolutionarily conserved glycerol shunt that hydrolyzes glucose-derived glycerol-3-phosphate to glycerol, coun...

2024-02-07 | MTBLS6847 | MetaboLights

Whole-Genome Sequencing of a Healthy Aging Cohort.

Studies of long-lived individuals have revealed few genetic mechanisms for protection against age-associated disease. Therefore, we pursued genome sequencing of a related phenotype-healthy aging-to understand the genetics of disease-free aging without medical intervention. In contrast with studies o...

EGAS00001002306 | EGA

The Functional and Anatomical Impacts of Healthy Muscle Ageing.

Not available

S-EPMC10604714 | biostudies-literature

Nutrition and Healthy Ageing in Asia: A Systematic Review.

Not available

S-EPMC10383719 | biostudies-literature

The World report on ageing and health: a policy framework for healthy ageing.

Not available

S-EPMC4848186 | biostudies-literature

Characteristics of older unpaid carers in England: a study of social patterning from the English Longitudinal Study of Ageing.

Not available

S-EPMC10945290 | biostudies-literature

Healthy ageing thymus

Single cell RNA sequencing of immune and non-immune cells from healthy ageing thymus Thymus is a primary lymphoid organ that creates an environment for the T lymphocyte precursors differentiation into the naive T cells, which involves TCR gene rearrangement, negative and positive selection. Despite...

EGAS00001004311 | EGA

Parental longevity predicts healthy ageing among women.

Not available

S-EPMC6201825 | biostudies-literature

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