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MetabolomicsProbabilistic networks of blood metabolites in healthy subjects as indicators of latent cardiovascular risk
The complex nature of the mechanisms behind cardiovascular diseases prevents the detection of latent early risk conditions. Network representations are ideally suited to investigate the complex interconnections between the individual components of a biological system underlying complex diseases. Her...
2015-01-01 | MTBLS147 | MetaboLights
MetabolomicsRapid biotransformation of STW 5 constituents by human gut microbiome from IBS- and non-IBS donors

STW 5, a blend of 9 medicinal plant extracts, exhibits promising efficacy in treating functional gastrointestinal disorders, notably irritable bowel syndrome (IBS). Nonetheless, its effects on the gastrointestinal microbiome and the role of microbiota on the conversion of its constituents are sti...

2024-05-07 | MTBLS2398 | MetaboLights
MetabolomicsUntargeted metabolomic analysis of human milk from healthy mothers reveals drivers of metabolite variability.
Understanding the human milk metabolome can help inform infant nutrition and health. Untargeted metabolomics was used to study breast milk from 31 healthy participants to assess the shared metabolites in milk from participants with various backgrounds and understand how different demographic, health...
2024-10-04 | MTBLS2419 | MetaboLights
ProteomicsSite-specific glycosylation mapping of Fc gamma receptor IIIb from neutrophils of individual healthy donors
The uploaded dateset corresponds to MS1 and MS2 spectra obtained for Fc gamma receptor IIIb isolated from neutrophils of individual healthy donors. They represent NA1/NA2, NA2/NA2, NA2/NA2 allotype respectively. Based on the data, the targeted analysis of the N-glycosylation has been performed for t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-08-05 | MSV000085913 | MassIVE
ProteomicsBlood plasma and serum samples of healthy donors fractionated on different chromatography sorbents
Blood as connective tissue potentially contain evidence of all processes occurring within the organism, at least in trace amounts. Because of their small size, peptides overcome cell membranes and epithelial barriers more freely than proteins. Among the peptides found in blood, there are both fragme...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-15 | MSV000081717 | MassIVE
ProteomicsReanalysis of the blood plasma and serum samples from healthy donors
Previously, we published a dataset of human blood plasma and serum samples of 10 healthy males and 10 healthy females, fractionated on a set of sorbents (cation exchange Toyopearl CM-650M, CM Bio-Gel A, SP Sephadex C-25 and anion exchange QAE Sephadex A-25) and analyzed by LC-MS/MS individually and ...
ORGANISM(S): Homo sapiens (Human) 
2024-06-14 | PXD027587 | Pride
Peptidomics Human microbiota Mass spectrometry Blood plasma and serum Healthy donors 
ProteomicsBlood plasma and serum samples of healthy donors fractionated on different chromatography sorbents
Blood as connective tissue potentially contain evidence of all processes occurring within the organism, at least in trace amounts. Because of their small size, peptides overcome cell membranes and epithelial barriers more freely than proteins. Among the peptides found in blood, there are both fragme...
ORGANISM(S): Homo sapiens (Human) 
2017-11-14 | PXD008141 | Pride
Peptidomics Mass-spectrometry Blood plasma and serum Norm Healthy donors 
TranscriptomicsTranscripts induced by exposure to SLE serum in healthy blood monocytes
Monocytes from 3 healthy donors were cultured for 6 hours in the presence of 20% serum from three newly diagnosed, untreated SLE patients. Microarray analysis was then performed upon normalizing the gene expression levels of samples incubated with SLE sera to those incubated with autologous serum. M...
ORGANISM(S): Homo sapiens 
2014-06-03 | E-GEOD-46920 | biostudies-arrayexpress
ProteomicsMass spectrometry analysis of the blood plasma and serum samples from healthy donors
Previously, we published a dataset of human blood plasma and serum samples of 10 healthy males and 10 healthy females, fractionated on a set of sorbents (cation exchange Toyopearl CM-650M, CM Bio-Gel A, SP Sephadex C-25 and anion exchange QAE Sephadex A-25) and analyzed by LC-MS/MS individually and ...
ORGANISM(S): Homo sapiens (Human) 
2024-06-14 | PXD027552 | Pride
Peptidomics Mass spectrometry Blood plasma and serum Healthy donors 
TranscriptomicsTranscripts differentially expressed in healthy blood mDCs compared to healthy monocytes
To directly compare the SLE monocyte transcriptional program with that of blood mDC precursors, we purified lineage HLA-DRhighCD11chigh mDCs and CD14+ monocytes from the blood of five healthy donors. Their gene expression profiles were then compared to those of blood SLE monocytes. An unsupervised c...
ORGANISM(S): Homo sapiens 
2014-06-03 | E-GEOD-46913 | biostudies-arrayexpress
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