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GenomicsEpiChip: Gene-by-gene quantification of epigenetic modification levels
Using datasets for the H3KAc histone modification in Th2 cells and an accompanying IgG control, we present an analysis strategy termed 'EpiChip' that alternates between single gene and global data distribution levels and allows a clear distinction between experimental background and signal. Examinat...
ORGANISM(S): Mus musculus 
2010-12-07 | E-GEOD-23092 | biostudies-arrayexpress
UnknownAnti-bias training for (sc)RNA-seq: experimental and computational approaches to improve precision.
Not available
S-EPMC8574610 | biostudies-literature
TranscriptomicsRNA sequencing reveals two major classes of gene expression levels in metazoan cells
The expression level of a gene is often used as a proxy for determining whether the protein or RNA product is functional in a cell or tissue. Therefore, it is of fundamental importance to understand the global distribution of gene expression levels, and to be able to interpret it mechanistically and...
ORGANISM(S): Mus musculus 
2011-04-16 | E-GEOD-28666 | biostudies-arrayexpress
TranscriptomicsTh single cell RNA-Seq
Th2 cells regulate helminth infections, allergic disorders, tumor immunity and pregnancy by secreting various cytokines. It is likely that there are undiscovered Th2-signaling molecules. While steroids are known to be immunoregulators, de novo steroid production from immune cells has not been previo...
ORGANISM(S): Mus musculus 
2014-04-25 | E-MTAB-2512 | biostudies-arrayexpress
TranscriptomicsImmune cell-specific Cyp11a1 deletion impairs inflammation resolution following LPS-induced acute lung injury in mice
Bulk RNA sequencing was performed on lung tissue from control and immune cell-specific Cyp11a1 conditional knockout (Cyp11a1fl/fl;Vav1Cre) mice following lipopolysaccharide (LPS)-induced acute lung injury. The experiment was designed to characterise genome-wide transcriptional changes associated wit...
ORGANISM(S): Mus musculus 
2026-09-15 | E-MTAB-17666 | biostudies-arrayexpress
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