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MetabolomicsLipidome Signatures of Metastasis in a Transgenic Mouse Model of Sonic Hedgehog Medulloblastoma.
Not available
ORGANISM(S): Mus musculus 
ST001290 | MetabolomicsWorkbench
TranscriptomicsTranscriptome along the hedgehog developing gut
Hox genes are required for the development of the intestinal caecum, a major organ of species eating plants. We have analysed the transcriptional regulation of Hoxd genes in caecal buds and show that they are controlled by a series of enhancers located in a gene desert telomeric to the HoxD cluster....
ORGANISM(S): Atelerix albiventris 
2013-10-23 | E-GEOD-44696 | biostudies-arrayexpress
TranscriptomicsExpression data from colon fibroblasts treated with Sonic hedgehog homolog (SHH)
Canonical Hedgehog (Hh) signaling regulates the expression of genes that are critical to the patterning and development of a variety of organ systems. In adult, both ligand-dependent and ligand-independent Hh pathway activation are known to promote tumorigenesis. Recent studies have shown that in tu...
ORGANISM(S): Homo sapiens 
2011-05-17 | E-GEOD-29316 | biostudies-arrayexpress
TranscriptomicsHistone deacetylase 6 exerts dichotomous effects on the Hedgehog signaling cascade
Murine embryo fibrablosts from stably transfected with Sonic Hedgehog were treated with siRNA and their transcription profiles captured.
ORGANISM(S): Mus_musculus 
2015-01-26 | E-MTAB-2440 | biostudies-arrayexpress
GenomicsHedgehog coronavirus 1
Hedgehog coronavirus 1 isolates: HTS genome sequencing
PRJNA1207786 | ENA
TranscriptomicsTranscriptional responses to Sonic Hedgehog pathway stimulation in in vitro derived neural progenitors
The objective of this study was to identify genes regulated by Sonic Hedgehog pathway stimulation in neural progenitors. Paired (parallel culture) triplicates of neuralized embryoid body cultures with and without Shh pathway stimulation (Ag1.3-treatment)
ORGANISM(S): Mus musculus 
2012-12-15 | E-GEOD-42565 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of conditional ablation of Indian hedgehog in the mouse uterus
Conditional ablation of Indian hedgehog (Ihh) in the murine uterus results in mice that are sterile due to defects in embryo implantation. We performed microarray analysis on these mice at the time point at which the Ihh target genes are induced by the administration of exogenous hormone to mimic d...
ORGANISM(S): Mus musculus 
2010-03-06 | E-GEOD-19517 | biostudies-arrayexpress
TranscriptomicsGene expression in mice with conditional over-activation of hedgehog signaling in the ovary
The objective of the study was to determine the cause of anovulation in transgenic mice with conditional over-activation of the hedgehog signaling pathway in the ovary. In Amhr2(cre/+)-SmoM2 transgenic mice, a constitutively active version of the hedgehog signal transducer, smoothened (SMO), known ...
ORGANISM(S): Mus musculus 
2012-03-14 | E-GEOD-35123 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of rat cerebellar granular neuronal precursor cells plated with Sonic Hedgehog (Shh) and then treated with the PKA activator DBA
Cerebellar granular neuronal precursors were plated in presence of Sonic Hedgehog (Shh) for 24h and then treated with the PKA activator Dibutyryl Cyclic Adenosine Monophosphate (DBA) for addittional 24h
ORGANISM(S): Rattus norvegicus 
2008-07-11 | E-MEXP-1668 | biostudies-arrayexpress
GenomicsAfrican pygmy hedgehog adenovirus 1
Genome Sequence of Adenovirus-1 Isolated from an African Pygmy Hedgehog
PRJDB8661 | ENA
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