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TranscriptomicsComparative transcriptome profiling analyses during the lag phase uncover YAP1, PDR1, PDR3, RPN4 and HSF1 as key regulatory genes in genomic adaptation to the lignocellulose derived inhitibor-stress for saccharomyces cerevisiae
The yeast Saccharomyces cerevisiae is able to adapt and in situ detoxify lignocellulose derived inhibitors such as furfural and HMF. The length of lag phase for cell growth in response to the inhibitor challenge has been used to measure tolerance of strain performance. Mechanisms of yeast tolerance ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-12-31 | E-GEOD-22939 | biostudies-arrayexpress
TranscriptomicsTranscriptomic impact of AWR5 effector expression in S. cerevisiae
The type III effector (T3E) AWR5 from the phytopathogen Ralstonia solanacearum causes disease in many plants relevant in agriculture. Heterologous expression in yeast of AWR5 from an integrated tetO promoter caused strong growth inhibition. In this series of experiments we investigate the possible c...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-31 | E-GEOD-70202 | biostudies-arrayexpress
TranscriptomicsMicroarray for suspension cells of PA14 WT with and without NE (50 uM and 500 uM) for 7 h
It has been proposed that the gastro-intestinal tract environment containing high levels of neuroendocrine hormones is important for gut-derived P. aeruginosa infections. In this study, we report that the hormone norepinephrine increases P. aeruginosa PA14 growth, virulence factor production, invasi...
ORGANISM(S): Pseudomonas aeruginosa UCBPP-PA14 
2009-08-27 | E-GEOD-13326 | biostudies-arrayexpress
TranscriptomicsEvidence that cryptic promoters occur extensively throughout the Saccharomyces cerevisiae genome
Microarray analysis was used to identify all cryptic promoters in the S. cerevisiae genome that are activated in spt6 and spt16 mutants. These experiments showed that cryptic initiation is widespread, occurring in approximately 1,000 genes. We generated 2 microarray profiles from fluor-rev...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-16 | E-GEOD-12272 | biostudies-arrayexpress
UnknownExploring breast cancer exosomes for novel biomarkers of potential diagnostic and prognostic importance.
Not available
S-EPMC9751250 | biostudies-literature
TranscriptomicsTranscription profiling of lapatinib treated of breast cancer cell lines
Dose and time course response of lapatinib in breast cancer cell lines.
ORGANISM(S): Homo sapiens 
2005-10-15 | E-MEXP-440 | biostudies-arrayexpress
TranscriptomicsIntegrated SV40 T/t-antigen Cancer Signature in Aggressive Breast, Prostate and Lung Carcinomas with Poor Prognosis
Understanding the genetic architecture of cancer pathways that distinguishes subsets of human cancer is critical to developing new therapies that better target tumors based upon their molecular expression profiles. In this study, we identify an integrated gene signature from multiple transgenic mo...
ORGANISM(S): Mus musculus 
2007-09-01 | E-GEOD-8666 | biostudies-arrayexpress
TranscriptomicsIntegrated SV40 T/t-antigen Cancer Signature in Aggressive Breast, Prostate and Lung Carcinomas with Poor Prognosis 1
Understanding the genetic architecture of cancer pathways that distinguishes subsets of human cancer is critical to developing new therapies that better target tumors based upon their molecular expression profiles. In this study, we identify an integrated gene signature from multiple transgenic mo...
ORGANISM(S): Mus musculus 
2007-09-01 | E-GEOD-8662 | biostudies-arrayexpress
TranscriptomicsIntegrated SV40 T/t-antigen Cancer Signature in Aggressive Breast, Prostate and Lung Carcinomas with Poor Prognosis 2
Understanding the genetic architecture of cancer pathways that distinguishes subsets of human cancer is critical to developing new therapies that better target tumors based upon their molecular expression profiles. In this study, we identify an integrated gene signature from multiple transgenic mo...
ORGANISM(S): Mus musculus 
2007-09-01 | E-GEOD-8663 | biostudies-arrayexpress
TranscriptomicsTP53 mutational status is a potential marker for risk stratification in Wilms tumour with diffuse anaplasia [expression]
The presence of diffuse anaplasia in Wilms tumours (DAWT) is associated with TP53 mutations and poor outcome. As patients receive intensified treatment, we sought to identify whether TP53 mutational status confers additional prognostic information. We studied 40 patients with DAWT with anaplasia in ...
ORGANISM(S): Homo sapiens 
2014-08-30 | E-GEOD-60850 | biostudies-arrayexpress
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