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TranscriptomicsTranscription profiling of human glioblastoma samples from a homogenous cohort of patients treated within clinical trial with eitehr radiotherapy or radiotherapy and temonzolomide
Analysis of 80 glioblastoma specimen of patients treated within clinical trials and 4 samples of "normal" brain tissue (non-tumoral). The data was used to identify factors of resistance to a chemoradiation therapy protocol of radiotherapy and concomitant and adjuvant temozolomide (alkylating agen...
ORGANISM(S): Homo sapiens 
2008-10-18 | E-GEOD-7696 | biostudies-arrayexpress
UnknownDoes Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma.
Not available
S-EPMC5070573 | biostudies-literature
UnknownDose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
Not available
S-EPMC3816958 | biostudies-literature
TranscriptomicsBAC aCGH profiling of 64 GBM (primary & recurrent)
aCGH was used to profile copy-number aberrations (CNA) in 64 glioblastoma specimen of patients treated within clinical trials. The data was used to identify changes in CNA which contribute to the aberrant of expression of HOX transcription factors. Our group had previously demonstrated that expressi...
ORGANISM(S): Homo sapiens 
2015-01-06 | E-GEOD-60507 | biostudies-arrayexpress
GenomicsGenome-wide DNA-methylation assessment by MethylCap-seq and Infinium HumanMethylation450 BeadChips: an independent large-scale comparison
DNA-methylation is an important epigenetic feature in health and disease. Two cost-efficient genome-scale methodologies to assess DNA-methylation are MethylCap-seq and Illumina's Infinium HumanMethylation450 BeadChips (HM450). However, objective information regarding the best-suited methodology for ...
EGAS00001001191 | EGA
TranscriptomicsGenome-wide DNA methylation profiling of 68 GBM (primary & recurrent), 4 glioma spheres and 5 non-tumor brain samples
DNA methylation analysis of 68 glioblastoma specimen of patients treated within clinical trials, 5 samples of normal brain tissue (non-tumor brain) and 4 tumor-derived glioma sphere lines. The data was used to identify changes in DNA methylation which contribute to the aberrant of expression of HOX ...
ORGANISM(S): Homo sapiens 
2015-01-06 | E-GEOD-60274 | biostudies-arrayexpress
TranscriptomicsExpression data from WIF1 induced LN-229 (GBM cell line)
Glioblastoma is the most aggressive primary brain tumor in adults and due to the invasive nature it cannot be completely removed. We have recently shown that the WNT inhibitory factor 1 (WIF1), a secreted inhibitor of WNTs, is downregulated in glioblastoma and acts as strong tumor suppressor. In sea...
ORGANISM(S): Homo sapiens 
2015-02-23 | E-GEOD-58525 | biostudies-arrayexpress
Genomicsena-DATASET-EORTC-22-06-2015-15:48:20:114-204 - samples
Data represent genome-wide DNA methylation profiles obtained by MethylCap-seq (Diagenode’s MethylCap-kit based purification followed by Illumina GAIIx sequencing), for 70 brain tissue samples, including 65 glioblastoma samples and 5 non-tumoral tissues (obtained from epilepsy surgery).
EGAD00001001399 | EGA
GenomicsEORTC Data Sharing DAC
Data Access Committee EGAC00001001818
EGAC00001001818 | EGA
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