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ProteomicsA core UPS molecular complement implicates unique endocytic compartments at the parasite-host interface in Giardia lamblia – native IP conditions
Affinity purification and mass spectrometry coupled to microscopy-based subcellular localization and signal correlation quantification techniques were employed to investigate protein complexes of eleven reported unconventionally-secreted putative and confirmed virulence factors of Giardia lamblia, a...
ORGANISM(S): Giardia intestinalis assemblage A 
2022-07-15 | PXD035190 | Pride
Giardia lamblia Virulence Unconventional protein secretion Peripheral endocytic compartments Interactome 
UnknownGastric Pouch Resizing for Recurrent Weight Gain After Roux-en-Y Gastric Bypass-Does It Have Its Rational?
Not available
S-EPMC11671430 | biostudies-literature
ProteomicsA core UPS molecular complement implicates unique endocytic compartments at the parasite-host interface in Giardia lamblia – crosslinking IP conditions
Affinity purification and mass spectrometry coupled to microscopy-based subcellular localization and signal correlation quantification techniques were employed to investigate protein complexes of eleven reported unconventionally-secreted putative and confirmed virulence factors of Giardia lamblia, a...
ORGANISM(S): Giardia intestinalis assemblage A 
2022-07-15 | PXD035195 | Pride
Giardia lamblia Virulence Unconventional protein secretion Peripheral endocytic compartments Interactome 
MetabolomicsPantothenate biosynthesis is critical for chronic infection by the neurotropic parasite Toxoplasma gondii
Coenzyme A (CoA) is an essential molecule acting in metabolism, post-translational modification, and regulation of gene expression. While all organisms synthesize CoA, many, including humans, are unable to produce its precursor, pantothenate. Intriguingly, like most plants, fungi and bacteria, paras...
2022-03-21 | MTBLS2501 | MetaboLights
ProteomicsProteomic analysis of Giardia lamblia ESV and PV organelle enriched fractions
The protozoan Giardia lamblia is a unique biological model to investigate minimal cellular mechanisms because it is an early‐diverged eukaryote that has undergone reductive evolution and has minimized or lost organelles such as mitochondria, peroxisomes, the endo-lysosomal system and a Golgi apparat...
ORGANISM(S): Giardia lamblia ATCC 50803 
2014-03-11 | PXD000694 | Pride
Flow cytometry assisted organelle sorting Organelle proteomics Giardia Encystation Endocytosis 
ProteomicsToxoplasma gondii aspartyl protease 3
The micronemes and rhoptries are specialized organelles that secrete their contents at the apical tip of apicomplexan parasites in a sequential and regulated manner. Microneme and rhoptry proteins crucially participate in motility, invasion, and egress from infected cells. They first traffic through...
ORGANISM(S): Toxoplasma gondii 
2018-01-30 | PXD006235 | Pride
Protease substrate screen Positional proteomics Tails 
UnknownA streamlined CRISPR/Cas9 approach for fast genome editing in Toxoplasma gondii and Besnoitia besnoiti.
Not available
S-EPMC7865079 | biostudies-literature
UnknownDiscovery of a tyrosine-rich sporocyst wall protein in Eimeria tenella.
Not available
S-EPMC4776368 | biostudies-literature
UnknownThe surface of Toxoplasma tachyzoites is dominated by a family of glycosylphosphatidylinositol-anchored antigens related to SAG1.
Not available
S-EPMC108187 | biostudies-literature
ProteomicsSerial co-immunoprecipitation to expand the protein interactome of the outer mitosomal membrane in Giardia lamblia
Giardia lamblia's outer mitosomal membrane protein repertoire was investigated using a series of co-immunoprecipitations which led to the discovery of novel associated components. This was assembled into a Giardia mitosomal protein interactome which expands beyond the organelle, reaching out to othe...
ORGANISM(S): Giardia lamblia ATCC 50803 
2016-11-15 | PXD004583 | Pride
Crosslinking Protein discovery 
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