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TranscriptomicsDifferential gene expression in ahr-1 mutants compared to wild-type C. elegans
The aryl hydrocarbon receptor (AHR) functions in higher organisims in development, metabolism and toxic responses. Its Caenorhabditis elegans (C. elegans) ortholog, AHR-1, facilitates neuronal development, growth and movement. We investigated the effect of AHR mutation on the transcriptional profile...
ORGANISM(S): Caenorhabditis elegans 
2014-09-19 | E-GEOD-61537 | biostudies-arrayexpress
TranscriptomicsCharacterization of microRNA-offset RNAs in human embryonic stem cells (hESCs)
Small RNA molecules, including microRNAs (miRNAs), play critical roles in regulating pluripotency, proliferation and differentiation of embryonic stem cells. miRNA-offset RNAs (moRNAs) are similar in length to miRNAs, align to miRNA precursor (pre-miRNA) loci and are therefore believed to derive fro...
ORGANISM(S): Homo sapiens 
2015-02-01 | E-GEOD-62501 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mice overexpressing spermidine/spermine N1-acetyltransferase (SSAT)
Type 2 diabetes is a complex disorder due to defects in insulin secretion and insulin action. Therefore, we investigated mice overexpressing spermidine/spermine N1-acetyltransferase (SSAT) have reduced amount of white adipose tissue, high basal metabolic rate, improved glucose tolerance, high insul...
ORGANISM(S): Mus musculus 
2007-04-25 | E-MEXP-165 | biostudies-arrayexpress
TranscriptomicsGermline PTEN promoter variants affect the expression profile in breast tumors
Comparison of the tumors PTEN promoter variant carrier and non carrier gene expression profiles. Expression profiles of 10 breast cancer patients with PTEN promoter variant and 10 controls matches for histology, ER, PR, T, N, M, Grade, HER2, Ki67, and p53.
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-22652 | biostudies-arrayexpress
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