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ProteomicsProteogenomic systems analysis identifies targeted therapy resistance mechanisms in EGFR-mutated lung cancer
Cancer precision medicine largely relies on knowledge about genetic aberrations in tumors and next-generation-sequencing studies have shown a high mutational complexity in many cancers. Although a large number of the observed mutations is believed to be not causally linked with cancer, the functiona...
ORGANISM(S): Homo sapiens (Human) 
2018-07-02 | PXD009996 | Pride
Lung cancer Proteomic System biology Drug resistance 
TranscriptomicsHepatocellular carcinomas (HCC) in mice transduced in utero with feline immunodeficiency virus-based vectors (CGH)
Fetal mice (16 days gestation) were administered FIV-based lentiviral viral particles containing the gene encoding EGFP. Six liver tumors developed in three mice (1 male, 2 females) between the ages of 273 and 484 days, each mouse developed 2 tumors. These tumors and non-tumorous liver tissue from ...
ORGANISM(S): Mus musculus 
2013-09-11 | E-GEOD-25900 | biostudies-arrayexpress
TranscriptomicsHepatocellular carcinomas (HCC) in mice transduced in utero with feline immunodeficiency virus-based vectors (expression)
Fetal mice (16 days gestation) were administered feline immunodeficiency virus (FIV)-based lentiviral viral particles containing the gene encoding GFP. Six liver tumors developed in three mice between the ages of 273 and 484 days, each mouse developed 2 tumors. These tumors and non-tumorous liver t...
ORGANISM(S): Mus musculus 
2013-09-11 | E-GEOD-19306 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver response to a glucose challenge in healthy and insulin resistant C57BL/6J mice
The goal of this experiment is to compare the transcriptional response to a metabolic stressor (glucose bolus) between healthy and insulin resistant mouse liver. Mice with an isogenic background (C57BL/6J mice) were fed diets for 12 weeks containing either 10 or 45% fat by energy (mainly palm oil) a...
ORGANISM(S): Mus musculus 
2012-03-21 | E-MTAB-601 | biostudies-arrayexpress
UnknownClinicopathological Spectrum and Treatment Outcomes of Cryofibrinogen-Associated Nephropathies.
Not available
S-EPMC12799572 | biostudies-literature
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