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We report the results of chromatin immunoprecipitation following by high-thoughput tag sequencing (ChIP-Seq) using the GA II platform from Illumina for the human transcription factor STAT1 in HeLa S3 cells. The STAT1 ChIP was performed using HeLa S3 cells that are stimulated using gamma-interferon. ...
ORGANISM(S): Homo sapiens 
Mediator complex has been known as pivotal regulator of RNA polymerase II. Mediator complex has two CDK subunits in vertebrates, named CDK8 and CDK19. To elucidate functional difference between CDK8 and CDK19 in human cell, we employ siRNA mediate knockdown assay using HeLa S3 cell line. According ...
ORGANISM(S): Homo sapiens 
Mediator complex has been known as pivotal regulator of RNA polymerase II. Mediator complex has two CDK subunits in vertebrates, named CDK8 and CDK19. To elucidate functional difference between CDK8 and CDK19 in human cell, we employ siRNA mediate knockdown assay using HeLa S3 cell line. According ...
ORGANISM(S): Homo sapiens 
Homo sapiens strain:Hela S3 Genome sequencing and assembly
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Homo sapiens 
We used ATLAS-seq to map the sites of integration of an engineered LINE-1 (L1) retrotransposon into the genome of HeLa S3 cells. Then, we compared the position of these sites with publicly available genomic datasets. In order to cross-corroborate our findings with datasets obtained in the same cell ...
ORGANISM(S): Homo sapiens 
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Homo sapiens 
We explored the relationship between the distribution of DNase I hypersensitive site(DHSs) and levels of gene expression. Expression values from 5 to 11 are raw log2 ratio-transformed data from gene expression arrays. We found that the distribution of DHSs in promoter region and CpG islands is posit...
ORGANISM(S): Homo sapiens 
LATS2 knockout causes PRC2 dysregulation and global H3K27me3 loss in HeLa-S3
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Homo sapiens 
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