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ProteomicsThe proteome of Pseudoramibacter alactolyticus and Anaerostipes caccae during lactate fermentation
Proteomic analysis of the chain elongating bacteria Pseudoramibacter alactolyticus and Anaerostipes caccae during lactate fermentation with supplemented acetic acetate. The impact of acetate absence on P. alactolyticus soluble proteome was also evaluated. (Principal investigator: Christopher Lawson,...
ORGANISM(S): Pseudoramibacter alactolyticus Anaerostipes caccae Bacteria 
2026-02-19 | PXD063079 | Pride
Lc-msms  chain elongating bacteria  medium chain fatty acids  lactate fermentation 
TranscriptomicsExogenous isoprene modulates gene expression in unstressed Arabidopsis thaliana plants
Isoprene is a well-studied volatile hemiterpene that protects plants from abiotic stress through mechanisms that are not fully understood. The antioxidant and membrane stabilizing potential of isoprene are the two most commonly invoked mechanisms. However, isoprene also affects phenylpropanoid metab...
ORGANISM(S): Arabidopsis thaliana 
2015-09-01 | E-GEOD-72547 | biostudies-arrayexpress
ProteomicsGendering Prehistory Through Science. Women and Early Social Complexity in Copper Age Iberia.
Given the absence of written records, the main source of information available to analyze gender inequalities in early complex societies is the human body itself. And yet, for decades, archaeologists have struggled with the identification of the sex of poorly preserved human remains. Here we present...
ORGANISM(S): Homo sapiens (Human) 
2023-07-06 | PXD038664 | Pride
Copper age Iberia Gender archaeology Enamel peptides Lc-ms/ms 
TranscriptomicsmiRNAs in ovarian cancer: A systems approach (miRNA data)
MicroRNAs (miRNAs) are short (~22 nucleotides) regulatory RNAs that can modulate gene expression and are aberrantly expressed in many diseases including cancer. We report the results of a systems analysis of miRNA regulation in ovarian cancer. We found that 33 miRNAs are up-regulated and 9 down-regu...
ORGANISM(S): Homo sapiens 
2011-07-28 | E-GEOD-23383 | biostudies-arrayexpress
MetabolomicsOverexpression of Brassica napus COMT1 in Arabidopsis heightens UV-B-mediated resistance to Plutella xylostella herbivory

UV-B radiation regulates numerous morphogenic, biochemical and physiological responses in plants, and can stimulate some responses typically associated with other abiotic and biotic stimuli, including invertebrate herbivory. Removal of UV-B from the growing environment of various plant species ha...

2023-08-14 | MTBLS8236 | MetaboLights
MetabolomicsMultiomic profiling of iron-deficient infant monkeys reveals alterations in neurologically important biochemicals in serum and cerebrospinal fluid before the onset of anemia

The effects of iron deficiency (ID) during infancy extend beyond the hematologic compartment and include short- and long-term adverse effects on many tissues including the brain. However, sensitive biomarkers of iron-dependent brain health are lacking in humans. To determine whether serum and cer...

2022-07-12 | MTBLS3388 | MetaboLights
MetabolomicsSoftware tool for internal standard based normalization of lipids, and effect of data-processing strategies on resulting values

BACKGROUND: Lipidomics, the comprehensive measurement of lipids within a biological system or substrate, is an emerging field with significant potential for improving clinical diagnosis and our understanding of health and disease. While lipids diverse biological roles contribute ...

2022-05-17 | MTBLS710 | MetaboLights
TranscriptomicsEffects of extensive fasting on hepatic transcription
Temporally restricted feeding has a profound effect on the hepatic circadian clock. While the circadian clock is largely unaffected by by extensive fasting, many transcripts are known to be affected by a fasting paradigm. This dataset shows the effect of extensive fasting on dynamic gene expression ...
ORGANISM(S): Mus musculus 
2009-11-23 | E-GEOD-13064 | biostudies-arrayexpress
TranscriptomicsThe effects of temporally restricted feeding on hepatic gene expression
Temporally restricted feeding is known to impact the circadian clock. This dataset shows the effects of temporally restricted feeding on the hepatic transcriptome. C57/B6 mice were entrained for two weeks to a temporally restricted feeding schedule. Food was made available only between ZT(CT)1 and Z...
ORGANISM(S): Mus musculus 
2009-11-23 | E-GEOD-13060 | biostudies-arrayexpress
MetabolomicsTwo UGT84A Family Glycosyltransferases Regulate Phenol, Flavonoid, and Tannin Metabolism in Juglans regia (English Walnut)
We showed previously that gallic acid is produced in walnut from 3-dehydroshikimate by a shikimate dehydrogenase (JrSkDH). This study focuses on the next step in the hydrolysable tannin pathway, the formation of 1-O-galloyl-β-D-glucose from the phenolic gallic acid and UDP glucose by a glycos...
2022-10-11 | MTBLS2042 | MetaboLights
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