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TranscriptomicsElucidating the Linezolid response of Staphylococcus aureus USA300 by a holistic study
The translation inhibitor Linezolid is an important antibiotic of last resort against multiresistant gram-positive pathogens including MRSA. Linezolid is reported to specifically inhibit extracellular virulence factors, but the molecular cause is unknown. To elucidate the physiological response of S...
ORGANISM(S): Staphylococcus aureus 
2016-02-22 | E-GEOD-65209 | biostudies-arrayexpress
TranscriptomicsDeletion of Rictor in brain and fat alters peripheral clock gene expression and increases blood pressure
The mammalian target of rapamycin complex 2 (mTORC2) contains the essential protein RICTOR and is activated by growth factors. mTORC2 in adipose tissue contributes to regulating glucose and lipid metabolism. In the perivascular adipose tissue (PVAT) mTORC2 ensures normal vascular reactivity by contr...
ORGANISM(S): Mus musculus 
2015-07-05 | E-GEOD-67077 | biostudies-arrayexpress
ProteomicsPeptide analysis in human cell lines via high-resolution MRM (PRM) for the annotation of non-canonical open reading frames
A major scientific drive is to characterize the protein-coding genome, which is a primary basis for studying human health. But the fundamental question remains: what has been missed in prior analyses? Over the past decade, the translation of non-canonical open reading frames (ncORFs) has been obse...
ORGANISM(S): Homo sapiens (Human) 
2026-02-17 | PXD066599 | Pride
Cell lines Mrmhr (prm) Human Non-canonical open reading frames 
MetabolomicsThe suberin transporter StABCG1 is required for barrier formation in potato leaves

Suberin is a hydrophobic biopolymer that acts as an internal and external diffusion and transpiration barrier in plants. It is involved in two phases of wound healing, i.e. initial closing layer formation and subsequent wound periderm development. Transcriptomic and metabolomic analyses of wounde...

2024-09-19 | MTBLS4823 | MetaboLights
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