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ProteomicsEpigenetic contributions to hemisphere asymmetry in healthy brain, aging, and Parkinson’s disease
Hemispheric asymmetry in neuronal processes is a fundamental feature of the human brain and drives symptom lateralization in Parkinson's disease (PD), but its molecular determinants are unknown. Here, we determine epigenetic changes and genes involved in hemispheric asymmetry in the healthy and PD b...
ORGANISM(S): Homo sapiens (Human) 
2020-03-26 | PXD015239 | Pride
Enhancer Neurons Epigenetics Parkinson’s disease Hemisphere asymmetry Aging 
GenomicsParkinson's disease (PD) genetic asymmetry in neuronal nuclei from paired hemisphere samples of prefrontal cortex
Parkinson's disease (PD) genetic asymmetry in neuronal nuclei from paired hemisphere samples of prefrontal cortex
PRJNA1100607 | ENA
GenomicsParkinson's disease (PD) genetic asymmetry in neuronal nuclei from paired hemisphere samples of prefrontal cortex (ATAC-Seq)
Parkinson's disease (PD) genetic asymmetry in neuronal nuclei from paired hemisphere samples of prefrontal cortex (ATAC-Seq)
PRJNA1103135 | ENA
UnknownHemisphere Asymmetry of Response to Pharmacologic Treatment in an Alzheimer's Disease Mouse Model.
Not available
S-EPMC4927832 | biostudies-literature
UnknownDecreased hemispheric connectivity and decreased intra- and inter- hemisphere asymmetry of resting state functional network connectivity in schizophrenia.
Not available
S-EPMC5651208 | biostudies-literature
TranscriptomicsParkinson's disease (PD) genetic asymmetry in neuronal nuclei from paired hemisphere samples of prefrontal cortex
We measured gene expression in neuronal nuclei from cortex derived from PD (18 male, 10 female) and healthy control (5 male, 6 female) brains. Each brain sample consisted of cortex from both right and left hemispheres. Th side of PD onset, age, duration of disease, as well as technical variables wer...
ORGANISM(S): Homo sapiens 
2026-03-12 | GSE264050 | GEO
Methylation profilingHemispheric asymmetry in the human brain and in Parkinson’s disease is linked to divergent epigenetic patterns in neurons
Background Hemispheric asymmetry in neuronal processes is a fundamental feature of the human brain and drives symptom lateralization in Parkinson's disease (PD), but its molecular determinants are unknown. Here, we identify divergent epigenetic patterns involved in hemispheric asymmetry by profiling...
ORGANISM(S): Homo sapiens 
2020-02-12 | GSE135037 | GEO
GenomicsHemispheric asymmetry in the human brain and in Parkinson’s disease is linked to divergent epigenetic patterns in neurons [RNA-seq]
Hemispheric asymmetry in the human brain and in Parkinson’s disease is linked to divergent epigenetic patterns in neurons [RNA-seq]
PRJNA557205 | ENA
Methylation profilingHemispheric asymmetry in the human brain and in Parkinson’s disease is linked to divergent epigenetic patterns in neurons [Bisulfite_Seq_discovery_cohort]
Background Hemispheric asymmetry in neuronal processes is a fundamental feature of the human brain and drives symptom lateralization in Parkinson's disease (PD), but its molecular determinants are unknown. Here, we identify divergent epigenetic patterns involved in hemispheric asymmetry by profiling...
ORGANISM(S): Homo sapiens 
2020-02-12 | GSE145153 | GEO
Methylation profilingHemispheric asymmetry in the human brain and in Parkinson’s disease is linked to divergent epigenetic patterns in neurons [Bisulfite_Seq_replication_cohort]
Background Hemispheric asymmetry in neuronal processes is a fundamental feature of the human brain and drives symptom lateralization in Parkinson's disease (PD), but its molecular determinants are unknown. Here, we identify divergent epigenetic patterns involved in hemispheric asymmetry by profiling...
ORGANISM(S): Homo sapiens 
2020-02-12 | GSE135035 | GEO
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