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MetabolomicsMFSD7C protects hemolysis-induced lung impairments by inhibiting ferroptosis

Hemolysis drives susceptibility to lung injury and predicts poor outcomes in diseases, such as malaria and sickle cell disease (SCD). However, the underlying pathological mechanism remains unknown. Here, we report that major facilitator superfamily domain containing 7C (MFSD7C) protects the lung ...

2024-09-06 | MTBLS9293 | MetaboLights
ModelsCaruso2020 - Activation of the alternative complement pathway and effects on hemolysis
This model is based on the publication: Caruso A, Vollmer J, Machacek M, Kortvely E. "Modeling the activation of the alternative complement pathway and its effects on hemolysis in health and disease." PLoS Comput Biol. 2020 Oct 2;16(10):e1008139. doi: 10.1371/journal.pcbi.1008139 Curation Comment: ...
2021-09-11 | MODEL2109110001 | BioModels
GenomicsMFSD7C protects hemolysis-induced lung impairments by inhibiting ferroptosis
MFSD7C protects hemolysis-induced lung impairments by inhibiting ferroptosis
PRJNA1062043 | ENA
GenomicsSecreted Phospholipase PLA2G5 Acts as a Self-Venom in Sepsis by Mediating Hemolysis
Secreted Phospholipase PLA2G5 Acts as a Self-Venom in Sepsis by Mediating Hemolysis
PRJNA1063735 | ENA
GenomicsHemolysis in the spleen facilitates erythrocyte turnover
Hemolysis in the spleen facilitates erythrocyte turnover
PRJNA497894 | ENA
TranscriptomicsMFSD7C protects hemolysis-induced lung impairments by inhibiting ferroptosis
Hemolysis drives susceptibility to lung injury and predicts poor outcomes in diseases, such as malaria and sickle cell disease (SCD). However, the underlying pathological mechanism remains unknown. Here, we report that major facilitator superfamily domain containing 7C (MFSD7C) protects the lung fro...
ORGANISM(S): Homo sapiens 
2024-02-08 | GSE252686 | GEO
UnknownHemolysis induced by PMIVSD occluder.
Not available
S-EPMC5067760 | biostudies-literature
TranscriptomicsSecreted Phospholipase PLA2G5 Acts as a Self-Venom in Sepsis by Mediating Hemolysis
Sepsis is a systemic response to infection with life-threatening consequences such as hemolysis, a predictor of mortality risks for the disease. Here, by measuring organism-wide changes in gene expression, we discovered that the secreted phospholipase PLA2G5 is induced in colon cell types during sep...
ORGANISM(S): Mus musculus 
2024-01-11 | GSE253060 | GEO
UnknownEvidence for alcohol-mediated hemolysis and erythrophagocytosis.
Not available
S-EPMC12268204 | biostudies-literature
GenomicsHemolysis-induced hepatic ferroptosis following xenotransfusion of genetically modified pig red blood cells
Hemolysis-induced hepatic ferroptosis following xenotransfusion of genetically modified pig red blood cells
PRJNA1311028 | ENA
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