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UnknownBexicaserin for the treatment of seizures in developmental and epileptic encephalopathies: A phase 1b/2a trial (PACIFIC).
Not available
S-EPMC12927688 | biostudies-literature
TranscriptomicsTranscription profiling of expressed human chromosome 21 genes in transchromosomic mouse embryos carrying a freely segregating copy of Hsa21
Detection of expressed human chromosome 21 genes in transchromosomic mouse embryos carrying a freely segregating copy of Hsa21.
ORGANISM(S): Mus musculus 
2005-11-19 | E-MEXP-409 | biostudies-arrayexpress
UnknownProtocol for a phase 2, partially blinded, randomized trial assessing the safety and efficacy of sorfequiline or bedaquiline in combination with pretomanid and linezolid in adult participants with newly diagnosed, drug-sensitive, smear-positive pulmonary tuberculosis (NC-009).
Not available
S-EPMC12869905 | biostudies-literature
UnknownAn aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes.
Not available
S-EPMC1378183 | biostudies-literature
TranscriptomicsComparative Hi-C reveals that CTCF underlies evolution of chromosomal domain architecture.
Topological domains are key architectural building blocks of chromosomes in complex genomes. Their functional importance and evolutionary dynamics are however not well defined. Here we performed comparative Hi-C in liver cells from four mammalian species, and characterized the conservation and dive...
ORGANISM(S): Canis lupus familiaris 
2015-02-26 | E-GEOD-65126 | biostudies-arrayexpress
TranscriptomicsGene expression in Maize root region 1 at low water potential
Previous work showed that the maize primary root adapts to low water potential (-1.6 MPa) by maintaining longitudinal expansion in the apical 3 mm (region 1), whereas in the adjacent 4 mm (region 2) longitudinal expansion reaches a maximum in well-watered roots but is progressively inhibited at low ...
ORGANISM(S): Zea mays 
2010-05-26 | E-GEOD-9341 | biostudies-arrayexpress
UnknownLRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression.
Not available
S-EPMC10910783 | biostudies-literature
UnknownBoring but important: a self-transcendent purpose for learning fosters academic self-regulation.
Not available
S-EPMC4643833 | biostudies-literature
UnknownExtracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain.
Not available
S-EPMC5515392 | biostudies-literature
TranscriptomicsGenome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
5hmC and TET proteins have been implicated in stem cell biology and cancer, but information on the genome-wide distribution of 5hmC is limited. Here we describe two novel and specific approaches to profile the genomic localisation of 5hmC. The first approach, termed GLIB (GLucosylation, perIodate o...
ORGANISM(S): Mus musculus 
2011-04-21 | E-GEOD-28682 | biostudies-arrayexpress
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